Farma ets

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Drug used in acute asthmatic crisis providing immediate bronchodilation:

Albuterol

Typical for Codeine:

affect on cough center in CNS

Typical for Dextrometorphane 1) synthetic derivative of morphine 2) has a low addictive profile 3) antitussive drug 4) anesthetizes the receptors in the lungs 5) adverse effect is numbness of the tongue

1, 2, 3

Typical for Theophylline: 1) Decreases asthma symptoms 2) Possess anti-inflammatory activity 3) Has narrow therapeutic window 4) Antitussive opioid type drug 5) Has broad therapeutic window

1, 2, 3

Mechanism of action of corticosteroids:

Inhibition of phospholipase A2

Mechanism of action of Ipraropium:

Blockade of muscarinic receptors

Typical for cromolyne: 1) Is a prophylactic anti-inflammatory agent 2) Inhibits mast cell degranulation 3) Is bronchodilator 4) Is useful in managing an acute asthma attacks 5) Its short duration of action drug

1, 2, 5

Non typical for Montelukast:

inhibits cytochrome isoenzymes

Drugs affecting RATS system:

Lizinopril

Not typical for ACE inhibitors used in the treatment of hypertention:

reflexively increasing cardiac output

Typical for ACE blockers in HF : 1) increase cardiac afterload 2) blockade angiotenzin II syntesis 3) decrease the breakdown of norepinephrine 4) reduce cardiac preload 5) decrease the breakdown of bradikynin

2, 4, 5

Undesirable side effects of Hydralazine can be blocked by concomitant use of a:

diuretics, β-adrenergic blockers

Hydrochlorthiaside decrease urinary excretion of:

Ca+2

Loop diuretic:

Ethacrynic acid

Strongest diuretic action:

Loop diuretics

The efficacy of thiazides may be diminished with concomitant use of :

NSAIDs

The diuretics useful in treating idiopathic hypercalciuria:

Thiazides

Pantoprazole unlike Omeprazole:

available in intravenous formulations

Omeprzole decrease the effectiveness of clopidogrel because:

prevents convertion to active metabolite

Antihistamine drug with antiemetic activity:

Cyclizine

Mechanism of antiemetic action of Ondansetron:

block of 5HT3-serotonin receptors

Targeting receptors of antiemetic action of Dolasetron:

5HT3 serotonin

Antihistamines are often administered in combination with high-dose metoclopramide to reduce:

extrapyramidal reactions

Typical for lactulose: 1) semisynthetic disaccharide sugar 2) an osmotic laxative 3) hydrolyzed by Gl enzymes 4) degraded by colonic bacteria 5) emollient laxatives

1, 2, 4

Lactulose is also used for the treatment of hepatic encephalopathy, due to its ability to reduce:

ammonia level in collon

Inhibitor of folate absorption cause folate deficiency anemia:

Phenobarbital

Correct assertion:

Antagonist of Heparin is Protamine sulfate

Non-correct assertion for hypolipidemic drugs:

Niacin lower serum HDL and serum triglycerides

Drugs that decrease the effectiveness of Levothyroxine: 1) Phenytoin 2) Phenobarbital 3) Cimetidine 4) Rifampin 5) Ketoconazole

1, 2, 4

Most appropriate drug for a patient with hyperthyroidism in the first trimester of pregnancy:

Propylthiouracil

Drugs effective in blunting the widespread sympathetic stimulation that occurs in hyperthyroidism:

Propranolol

Non typical for desmopressin:

has significant anticoagulant activity

Establish compliance: I. Short-acting insulin II . Intermediate-acting insulin III Long-acting insulin a) Regular insulin b) Insulin isophane c) insulin glargine

I-a II-b III-c

Drugs that should be used concomitantly to prevent NSAID-induced ulcers: 1) Loperamide 2) Misoprostol 3) Ondansetron 4) Metoclopramide 5) Pantoprasol

2, 5

Aspirin should be used with caution in patients with asthma because:

increase leukotriene production

Antipseudomonal penicillin:

Piperacillin

Concentration-dependent killing antimicrobial agents:

Aminoglycosides

Typical for Raloxifene : 1) lowers low-density lipoprotein 2) decreases bone resorption 3) increases bone density 4) increases low-density lipoprotein 5) increases bone resorption 6) decreases bone density

1, 2, 3

Non typical for Clomiphene:

act as competitive androgen antaqonist

Typical for cotrimoxazole: 1) The combination of trimethoprim with sulfa drug 2) Prevents reduction of dihydrofolate to tetrahydrofolate 3) Inhibits the incorporation of PABA into dihydrofolic acid precursors 4) Poorly crosses the blood-brain barrier 5) The combination of trimethoprim with aminosalicylic acid

1, 2, 3

Typical for antigelmint Ivermectin: 1) acts on glutamate-gated chloride channel receptors 2) leads to chloride influx and hyperpolarization 3) increases the permeability of the cell membrane to calcium 4) increases release of acetylcholine and inhibition of cholinesterase 5) leads to sodium influx and depolarization

1, 2

Pentamidine: 1) stops polyamine production by inhibiting ornithine decarboxylase 2) interferes with the synthesis of RNA, DNA, phospholipids and proteins 3) reduces the permeability of the cell membrane to calcium 4) reacts with sulfhydryl groups of digestive enzymes 5) accumulates in the parasite via an energy-dependent, high-affinity uptake system

2, 5

Clomiphene :

partial estrogen agonist

Pyrantel pamoate in parasites organism: 1) inhibits glutamate-gated chloride channel receptors 2) decreases the permeability of the cell membrane to calcium 3) depolarizes as a neuromuscular-blocking agent 4) causes release of acetylcholine 5) inhibits of cholinesterase

3, 4, 5

Specify accordance between anticancer drugs and action mechanisms: I. Methotrexate -> II. Vinblastine -> 1) alkylating agent 2) monoclonal antibody 3) tyrosine kinase inhibitor 4) antimetabolite 5) microtubule inhibitor

I-4 II-5

Calculates the single dose of basic substance ( in gram) of1% 50 ml Aminocapronic acid solution. Rp. : Sol. Acidi Aminocapronici 1%- 100ml D. S. 50 ml for intravenous infusion during the first hour of treatment

0,5

Anticancer drug- micropubule inhibitors: 1) Docetaxel 2) Vincristine 3) Carmustine 4) Mitoxantrone 5) Lomustine

1, 2

Patient was started on anti-amoebic therapy for treatment of amebas. However, during the treatment, the patient had taken alcohol, which led to disulfiram-like intoxication. Which drug may be the reason of this reaction?

Metronidazole

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samnet net · 44問 · 1年前

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samnet net · 84問 · 1年前

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