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  • 問題数 48 • 1/1/2025

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    問題一覧

  • 1

    Drug used in acute asthmatic crisis providing immediate bronchodilation:

    Albuterol

  • 2

    Typical for Codeine:

    affect on cough center in CNS

  • 3

    Typical for Dextrometorphane 1) synthetic derivative of morphine 2) has a low addictive profile 3) antitussive drug 4) anesthetizes the receptors in the lungs 5) adverse effect is numbness of the tongue

    1, 2, 3

  • 4

    Typical for Theophylline: 1) Decreases asthma symptoms 2) Possess anti-inflammatory activity 3) Has narrow therapeutic window 4) Antitussive opioid type drug 5) Has broad therapeutic window

    1, 2, 3

  • 5

    Mechanism of action of corticosteroids:

    Inhibition of phospholipase A2

  • 6

    Mechanism of action of Ipraropium:

    Blockade of muscarinic receptors

  • 7

    Typical for cromolyne: 1) Is a prophylactic anti-inflammatory agent 2) Inhibits mast cell degranulation 3) Is bronchodilator 4) Is useful in managing an acute asthma attacks 5) Its short duration of action drug

    1, 2, 5

  • 8

    Non typical for Montelukast:

    inhibits cytochrome isoenzymes

  • 9

    Drugs affecting RATS system:

    Lizinopril

  • 10

    Not typical for ACE inhibitors used in the treatment of hypertention:

    reflexively increasing cardiac output

  • 11

    Typical for ACE blockers in HF : 1) increase cardiac afterload 2) blockade angiotenzin II syntesis 3) decrease the breakdown of norepinephrine 4) reduce cardiac preload 5) decrease the breakdown of bradikynin

    2, 4, 5

  • 12

    Undesirable side effects of Hydralazine can be blocked by concomitant use of a:

    diuretics, β-adrenergic blockers

  • 13

    Hydrochlorthiaside decrease urinary excretion of:

    Ca+2

  • 14

    Loop diuretic:

    Ethacrynic acid

  • 15

    Strongest diuretic action:

    Loop diuretics

  • 16

    The efficacy of thiazides may be diminished with concomitant use of :

    NSAIDs

  • 17

    The diuretics useful in treating idiopathic hypercalciuria:

    Thiazides

  • 18

    Pantoprazole unlike Omeprazole:

    available in intravenous formulations

  • 19

    Omeprzole decrease the effectiveness of clopidogrel because:

    prevents convertion to active metabolite

  • 20

    Antihistamine drug with antiemetic activity:

    Cyclizine

  • 21

    Mechanism of antiemetic action of Ondansetron:

    block of 5HT3-serotonin receptors

  • 22

    Targeting receptors of antiemetic action of Dolasetron:

    5HT3 serotonin

  • 23

    Antihistamines are often administered in combination with high-dose metoclopramide to reduce:

    extrapyramidal reactions

  • 24

    Typical for lactulose: 1) semisynthetic disaccharide sugar 2) an osmotic laxative 3) hydrolyzed by Gl enzymes 4) degraded by colonic bacteria 5) emollient laxatives

    1, 2, 4

  • 25

    Lactulose is also used for the treatment of hepatic encephalopathy, due to its ability to reduce:

    ammonia level in collon

  • 26

    Inhibitor of folate absorption cause folate deficiency anemia:

    Phenobarbital

  • 27

    Correct assertion:

    Antagonist of Heparin is Protamine sulfate

  • 28

    Non-correct assertion for hypolipidemic drugs:

    Niacin lower serum HDL and serum triglycerides

  • 29

    Drugs that decrease the effectiveness of Levothyroxine: 1) Phenytoin 2) Phenobarbital 3) Cimetidine 4) Rifampin 5) Ketoconazole

    1, 2, 4

  • 30

    Most appropriate drug for a patient with hyperthyroidism in the first trimester of pregnancy:

    Propylthiouracil

  • 31

    Drugs effective in blunting the widespread sympathetic stimulation that occurs in hyperthyroidism:

    Propranolol

  • 32

    Non typical for desmopressin:

    has significant anticoagulant activity

  • 33

    Establish compliance: I. Short-acting insulin II . Intermediate-acting insulin III Long-acting insulin a) Regular insulin b) Insulin isophane c) insulin glargine

    I-a II-b III-c

  • 34

    Drugs that should be used concomitantly to prevent NSAID-induced ulcers: 1) Loperamide 2) Misoprostol 3) Ondansetron 4) Metoclopramide 5) Pantoprasol

    2, 5

  • 35

    Aspirin should be used with caution in patients with asthma because:

    increase leukotriene production

  • 36

    Antipseudomonal penicillin:

    Piperacillin

  • 37

    Concentration-dependent killing antimicrobial agents:

    Aminoglycosides

  • 38

    Typical for Raloxifene : 1) lowers low-density lipoprotein 2) decreases bone resorption 3) increases bone density 4) increases low-density lipoprotein 5) increases bone resorption 6) decreases bone density

    1, 2, 3

  • 39

    Non typical for Clomiphene:

    act as competitive androgen antaqonist

  • 40

    Typical for cotrimoxazole: 1) The combination of trimethoprim with sulfa drug 2) Prevents reduction of dihydrofolate to tetrahydrofolate 3) Inhibits the incorporation of PABA into dihydrofolic acid precursors 4) Poorly crosses the blood-brain barrier 5) The combination of trimethoprim with aminosalicylic acid

    1, 2, 3

  • 41

    Typical for antigelmint Ivermectin: 1) acts on glutamate-gated chloride channel receptors 2) leads to chloride influx and hyperpolarization 3) increases the permeability of the cell membrane to calcium 4) increases release of acetylcholine and inhibition of cholinesterase 5) leads to sodium influx and depolarization

    1, 2

  • 42

    Pentamidine: 1) stops polyamine production by inhibiting ornithine decarboxylase 2) interferes with the synthesis of RNA, DNA, phospholipids and proteins 3) reduces the permeability of the cell membrane to calcium 4) reacts with sulfhydryl groups of digestive enzymes 5) accumulates in the parasite via an energy-dependent, high-affinity uptake system

    2, 5

  • 43

    Clomiphene :

    partial estrogen agonist

  • 44

    Pyrantel pamoate in parasites organism: 1) inhibits glutamate-gated chloride channel receptors 2) decreases the permeability of the cell membrane to calcium 3) depolarizes as a neuromuscular-blocking agent 4) causes release of acetylcholine 5) inhibits of cholinesterase

    3, 4, 5

  • 45

    Specify accordance between anticancer drugs and action mechanisms: I. Methotrexate -> II. Vinblastine -> 1) alkylating agent 2) monoclonal antibody 3) tyrosine kinase inhibitor 4) antimetabolite 5) microtubule inhibitor

    I-4 II-5

  • 46

    Calculates the single dose of basic substance ( in gram) of1% 50 ml Aminocapronic acid solution. Rp. : Sol. Acidi Aminocapronici 1%- 100ml D. S. 50 ml for intravenous infusion during the first hour of treatment

    0,5

  • 47

    Anticancer drug- micropubule inhibitors: 1) Docetaxel 2) Vincristine 3) Carmustine 4) Mitoxantrone 5) Lomustine

    1, 2

  • 48

    Patient was started on anti-amoebic therapy for treatment of amebas. However, during the treatment, the patient had taken alcohol, which led to disulfiram-like intoxication. Which drug may be the reason of this reaction?

    Metronidazole