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microbiology 101-200

microbiology 101-200
93問 • 2年前
  • samnet net
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  • 1

    Specific for endotoxins: 1) It is secreted by the microbial cell into the external environment 2) They do not have a selective effect on organs and tissues 3) They have a selective effect on organs and tissues 4) They do not turn into anatoxin (toxoid). 5) They become anatoxin (toxoid).

    2, 4

  • 2

    One of the most important biological effects of endotoxins is:

    fever reaction

  • 3

    The process by which bacteria stick to the surfaces of host cells. After bacteria have entered the body, adherence is a major initial step in the infection process. The terms adherence, adhesion, and attachment are often used interchangeably.

    adherence (adhesion, attachment)

  • 4

    The main transmission mechanism of the disease when the pathogens are localized in the upper respiratory tract:

    airborne droplets

  • 5

    Alimentary infection refers to what infection mechanism?

    fecal-oral

  • 6

    Contagion from items used by the patient belongs to which mechanism of infection?

    indirect contact

  • 7

    The condition of the normal microflora of the body is an infection caused by pathogenic representatives:

    endogenous infection

  • 8

    Several microorganisms are involved in the formation of infection:

    mixed infection

  • 9

    The addition of a new infectious process caused by another microorganism to the infection caused by one microorganism is called:

    secondary infection

  • 10

    Reinfection with the same pathogen without recovery from an infectious disease:

    superinfection

  • 11

    Persistence:

    long-term presence of the causative agent in the body

  • 12

    Persistence is accompanied by: 1) Microbial carrier 2) Acute infection 3) Exogenous infection 4) Chronic infection

    1, 4

  • 13

    The H antigen is:

    flagellum

  • 14

    The K antigen is:

    capsule

  • 15

    The K antigen is:

    glycocalyx

  • 16

    Superantigens action mechanism:

    Polyclonal activation of T-lymphocytes

  • 17

    Has superantigen activity:

    Toxic shock syndrome toxin of Staphylococcus aureus

  • 18

    Natural Acquired Immunity:

    is formed after the disease

  • 19

    Antigen presentation:

    presentation of information about the antigen to T- and B-lymphocytes

  • 20

    Antigen presentation:

    antigenic components are presented to T-helpers in complex with class II MHC

  • 21

    It does not belong to the main characteristics of antigens:

    competence

  • 22

    What is an epitope?

    antigenic determinant

  • 23

    Involved in the oxygen-dependent mechanism of phagocytosis:

    hydrogen peroxide

  • 24

    Antigen presenting cells refer to:

    macrophages

  • 25

    Superantigens:

    are antigens that can activate T-helpers without undergoing processing

  • 26

    Refers to virus antigens:

    S-antigen

  • 27

    MHC class I antigens:

    is individual for each organism

  • 28

    MHC class II antigens are located in:

    mainly in the membrane of immunocompetent cells

  • 29

    Does not apply to immunocompetent cells: 1) T-lymphocytes 2) B-lymphocytes 3) Erythrocytes 4) Macrophages 5) Hepatocytes

    3, 5

  • 30

    T-helpers:

    receives information about the antigen from the antigen-presenting cell

  • 31

    Fab-fragment of immunoglobulin molecule:

    provides binding to specific antigen

  • 32

    An immunoglobulin that can pass from the placenta is:

    İgG

  • 33

    The detection of IgM against a certain pathogen in the blood serum of newborns confirms: ,

    intrauterine infection

  • 34

    The detection of Ig G against a certain pathogen in the blood serum of newborns confirms:

    that the mother has a relevant disease

  • 35

    How many idiotypes can an immunoglobulin of the same class have?

    endless

  • 36

    Immune complexes:

    is formed by the combination of antigen and specific antibody

  • 37

    Memory cells are formed from which cells:

    from both T- and B-lymphocytes

  • 38

    The result of serological reactions is evaluated:

    based on the formation of an antigen-antibody complex

  • 39

    The immediate, nonspecific response to a pathogen, the components of this response include phagocytic cells (macrophages and neutrophils), NK cells, TLRs, cytokines, and complement is:

    Innate immunity

  • 40

    The destructive effect of T-killers on target cells is related to:

    by lysis of target cells

  • 41

    Perforin, granzyme and granulysin:

    They are cytotoxic substances of T-killers

  • 42

    The antigen binding center of the immunoglobulin molecule is formed:

    Between the hypervariable domains of the L and H chain

  • 43

    What is indicated by 1 in the structural scheme of the immunoglobulin molecule?

    Fab-fragment

  • 44

    What is indicated by 2 in the structural scheme of the immunoglobulin molecule?

    Fc-fragment

  • 45

    What is indicated by 5 in the structural scheme of the immunoglobulin molecule?

    active center

  • 46

    Fc-fragment of immunoglobulin molecule:

    provides attachment to the surface of lymphocytes

  • 47

    Fc-fragment molecule of immunoglobulin:

    provides connection with the complement

  • 48

    Which of these has a pentamer structure:

    IgM

  • 49

    Which immunoglobulin is depicted in the picture?

    IgM

  • 50

    On the surface of immune cells there are receptors for these immunoglobulins: 1) IgG 2) IgM 3) IgA 4) IgE 5) IgD

    2, 5

  • 51

    The dominant antibody in the primary immune response is:

    IgM

  • 52

    It is an immunoglobulin with a secretory component:

    IgA

  • 53

    Monoclonal antibodies:

    are antibodies synthesized by a B-lymphocyte clone

  • 54

    Used to get monoclonal antibodies:

    hybridomas

  • 55

    What are the differences between monoclonal antibodies and polyclonal antibodies?

    with strict specificity

  • 56

    It ensures the conversion of haptens into complete antigens:

    their association with proteins

  • 57

    When a proteolytic enzyme (papain) acts on an immunoglobulin (IgG) molecule:

    breaks down with the formation of two Fab-fragments and one Fc-fragment

  • 58

    Passes through the placenta:

    IgG

  • 59

    Cytophilic immunoglobulins: 1) IgG 2) IgM 3) IgA 4) IgE 5) IgD

    1, 4

  • 60

    Immunoglobulin with a secretory component:

    IgA

  • 61

    Secretory component of immunoglobulin A:

    protects it from destruction under the action of the secrets of the mucous membranes

  • 62

    Immunoglobulins involved in immediate hypersensitivity reactions: 1) IgG 2) IgM 3) IgA 4) IgE 5) IgD

    1, 4

  • 63

    Immune complexes:

    are formed as a result of the combination of a specific antigen with an antibody

  • 64

    Incomplete antibodies:

    have one active site

  • 65

    Attachment of an antigen to an incomplete antibody occurs:

    his blockade

  • 66

    On what is the principle of revaccination based?

    the secondary immune response is accompanied by the formation of antibodies in high titers

  • 67

    Participate in a specific humoral immune response:

    antibodies

  • 68

    Mechanism of humoral specific immune response:

    neutralization of antigens by specific antibodies

  • 69

    Participate in a specific cellular immune response:

    T-killers

  • 70

    Mechanism of specific cellular immune response:

    cytotoxic killing of target cells

  • 71

    When the immune system meets the same antigen again, the most effective reactions are provided by:

    immunological memory

  • 72

    From what cells are memory cells formed?

    from T- and B-lymphocytes

  • 73

    How do memory cells differ from other lymphocytes from a morphological point of view?

    do not differ

  • 74

    Serological reactions are not typical for:

    occurs between antigen and specific lymphocytes

  • 75

    Serological diagnosis is based on:

    detection of specific antibodies or antigen in the patient's blood serum

  • 76

    Agglutination reaction is detected by:

    sediment

  • 77

    Agglutination of bacteria without flagella is called:

    O-agglutination

  • 78

    Agglutination of bacteria with flagella is called:

    H-agglutination

  • 79

    For the agglutination reaction, use: 1) Meat-peptone broth; 2) Diagnosticum; 3) physiological solution; 4) Immune serum; 5) Lugol's solution;

    2, 3, 4

  • 80

    The agglutination test was performed with dilutions of serum 1:50; 1:100; 1:200; 1:400; 1:800. When evaluating the results in all dilutions, as well as in the control, a positive reaction was observed. What is the titer of the agglutination reaction?

    the reaction is set incorrectly

  • 81

    The agglutination reaction was performed with serum dilutions in ratios of 1:50; 1:100; 1:200; 1:400; 1:800. When evaluating the results, a positive reaction was observed in dilutions of 1:50; 1:100; 1:200; 1:400. In test tubes with dilutions of 1:800 and in the control, agglutination was not observed. Serum agglutinating titer:

    1:400

  • 82

    Diagnostic titer of agglutinating serum:

    titer confirming the disease

  • 83

    An agglutination reaction in which erythrocytes with antigens adsorbed on them are used as a diagnosticum is called:

    indirect hemagglutination reaction

  • 84

    In an indirect hemagglutination reaction, the following is used as a diagnosticum:

    erythrocytes with antigens adsorbed on them

  • 85

    Hemagglutination inhibition reaction is used for:

    virus identification

  • 86

    The Coombs reaction is used for:

    detection of incomplete antibodies detection of antibodies

  • 87

    Used to detect incomplete antibodies:

    Coombs reaction

  • 88

    Anti-human (antiglobulin) antibodies are used in:

    Coombs reactions

  • 89

    Precipitation reaction is determined by:

    the appearance of turbidity

  • 90

    The directed movement of leukocytes up a gradient concentration toward the site of infection. This movement is

    Chemotaxis

  • 91

    The agglutination reaction is manifested by:

    with the formation of sediment

  • 92

    The inhibation of hemagglutination reaction is used:

    in the identification of viruses

  • 93

    Enzyme-Linked Immunosorbent Assay is based on:

    detection of the corresponding antigen with the help of antibodies labeled with enzymes

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    問題一覧

  • 1

    Specific for endotoxins: 1) It is secreted by the microbial cell into the external environment 2) They do not have a selective effect on organs and tissues 3) They have a selective effect on organs and tissues 4) They do not turn into anatoxin (toxoid). 5) They become anatoxin (toxoid).

    2, 4

  • 2

    One of the most important biological effects of endotoxins is:

    fever reaction

  • 3

    The process by which bacteria stick to the surfaces of host cells. After bacteria have entered the body, adherence is a major initial step in the infection process. The terms adherence, adhesion, and attachment are often used interchangeably.

    adherence (adhesion, attachment)

  • 4

    The main transmission mechanism of the disease when the pathogens are localized in the upper respiratory tract:

    airborne droplets

  • 5

    Alimentary infection refers to what infection mechanism?

    fecal-oral

  • 6

    Contagion from items used by the patient belongs to which mechanism of infection?

    indirect contact

  • 7

    The condition of the normal microflora of the body is an infection caused by pathogenic representatives:

    endogenous infection

  • 8

    Several microorganisms are involved in the formation of infection:

    mixed infection

  • 9

    The addition of a new infectious process caused by another microorganism to the infection caused by one microorganism is called:

    secondary infection

  • 10

    Reinfection with the same pathogen without recovery from an infectious disease:

    superinfection

  • 11

    Persistence:

    long-term presence of the causative agent in the body

  • 12

    Persistence is accompanied by: 1) Microbial carrier 2) Acute infection 3) Exogenous infection 4) Chronic infection

    1, 4

  • 13

    The H antigen is:

    flagellum

  • 14

    The K antigen is:

    capsule

  • 15

    The K antigen is:

    glycocalyx

  • 16

    Superantigens action mechanism:

    Polyclonal activation of T-lymphocytes

  • 17

    Has superantigen activity:

    Toxic shock syndrome toxin of Staphylococcus aureus

  • 18

    Natural Acquired Immunity:

    is formed after the disease

  • 19

    Antigen presentation:

    presentation of information about the antigen to T- and B-lymphocytes

  • 20

    Antigen presentation:

    antigenic components are presented to T-helpers in complex with class II MHC

  • 21

    It does not belong to the main characteristics of antigens:

    competence

  • 22

    What is an epitope?

    antigenic determinant

  • 23

    Involved in the oxygen-dependent mechanism of phagocytosis:

    hydrogen peroxide

  • 24

    Antigen presenting cells refer to:

    macrophages

  • 25

    Superantigens:

    are antigens that can activate T-helpers without undergoing processing

  • 26

    Refers to virus antigens:

    S-antigen

  • 27

    MHC class I antigens:

    is individual for each organism

  • 28

    MHC class II antigens are located in:

    mainly in the membrane of immunocompetent cells

  • 29

    Does not apply to immunocompetent cells: 1) T-lymphocytes 2) B-lymphocytes 3) Erythrocytes 4) Macrophages 5) Hepatocytes

    3, 5

  • 30

    T-helpers:

    receives information about the antigen from the antigen-presenting cell

  • 31

    Fab-fragment of immunoglobulin molecule:

    provides binding to specific antigen

  • 32

    An immunoglobulin that can pass from the placenta is:

    İgG

  • 33

    The detection of IgM against a certain pathogen in the blood serum of newborns confirms: ,

    intrauterine infection

  • 34

    The detection of Ig G against a certain pathogen in the blood serum of newborns confirms:

    that the mother has a relevant disease

  • 35

    How many idiotypes can an immunoglobulin of the same class have?

    endless

  • 36

    Immune complexes:

    is formed by the combination of antigen and specific antibody

  • 37

    Memory cells are formed from which cells:

    from both T- and B-lymphocytes

  • 38

    The result of serological reactions is evaluated:

    based on the formation of an antigen-antibody complex

  • 39

    The immediate, nonspecific response to a pathogen, the components of this response include phagocytic cells (macrophages and neutrophils), NK cells, TLRs, cytokines, and complement is:

    Innate immunity

  • 40

    The destructive effect of T-killers on target cells is related to:

    by lysis of target cells

  • 41

    Perforin, granzyme and granulysin:

    They are cytotoxic substances of T-killers

  • 42

    The antigen binding center of the immunoglobulin molecule is formed:

    Between the hypervariable domains of the L and H chain

  • 43

    What is indicated by 1 in the structural scheme of the immunoglobulin molecule?

    Fab-fragment

  • 44

    What is indicated by 2 in the structural scheme of the immunoglobulin molecule?

    Fc-fragment

  • 45

    What is indicated by 5 in the structural scheme of the immunoglobulin molecule?

    active center

  • 46

    Fc-fragment of immunoglobulin molecule:

    provides attachment to the surface of lymphocytes

  • 47

    Fc-fragment molecule of immunoglobulin:

    provides connection with the complement

  • 48

    Which of these has a pentamer structure:

    IgM

  • 49

    Which immunoglobulin is depicted in the picture?

    IgM

  • 50

    On the surface of immune cells there are receptors for these immunoglobulins: 1) IgG 2) IgM 3) IgA 4) IgE 5) IgD

    2, 5

  • 51

    The dominant antibody in the primary immune response is:

    IgM

  • 52

    It is an immunoglobulin with a secretory component:

    IgA

  • 53

    Monoclonal antibodies:

    are antibodies synthesized by a B-lymphocyte clone

  • 54

    Used to get monoclonal antibodies:

    hybridomas

  • 55

    What are the differences between monoclonal antibodies and polyclonal antibodies?

    with strict specificity

  • 56

    It ensures the conversion of haptens into complete antigens:

    their association with proteins

  • 57

    When a proteolytic enzyme (papain) acts on an immunoglobulin (IgG) molecule:

    breaks down with the formation of two Fab-fragments and one Fc-fragment

  • 58

    Passes through the placenta:

    IgG

  • 59

    Cytophilic immunoglobulins: 1) IgG 2) IgM 3) IgA 4) IgE 5) IgD

    1, 4

  • 60

    Immunoglobulin with a secretory component:

    IgA

  • 61

    Secretory component of immunoglobulin A:

    protects it from destruction under the action of the secrets of the mucous membranes

  • 62

    Immunoglobulins involved in immediate hypersensitivity reactions: 1) IgG 2) IgM 3) IgA 4) IgE 5) IgD

    1, 4

  • 63

    Immune complexes:

    are formed as a result of the combination of a specific antigen with an antibody

  • 64

    Incomplete antibodies:

    have one active site

  • 65

    Attachment of an antigen to an incomplete antibody occurs:

    his blockade

  • 66

    On what is the principle of revaccination based?

    the secondary immune response is accompanied by the formation of antibodies in high titers

  • 67

    Participate in a specific humoral immune response:

    antibodies

  • 68

    Mechanism of humoral specific immune response:

    neutralization of antigens by specific antibodies

  • 69

    Participate in a specific cellular immune response:

    T-killers

  • 70

    Mechanism of specific cellular immune response:

    cytotoxic killing of target cells

  • 71

    When the immune system meets the same antigen again, the most effective reactions are provided by:

    immunological memory

  • 72

    From what cells are memory cells formed?

    from T- and B-lymphocytes

  • 73

    How do memory cells differ from other lymphocytes from a morphological point of view?

    do not differ

  • 74

    Serological reactions are not typical for:

    occurs between antigen and specific lymphocytes

  • 75

    Serological diagnosis is based on:

    detection of specific antibodies or antigen in the patient's blood serum

  • 76

    Agglutination reaction is detected by:

    sediment

  • 77

    Agglutination of bacteria without flagella is called:

    O-agglutination

  • 78

    Agglutination of bacteria with flagella is called:

    H-agglutination

  • 79

    For the agglutination reaction, use: 1) Meat-peptone broth; 2) Diagnosticum; 3) physiological solution; 4) Immune serum; 5) Lugol's solution;

    2, 3, 4

  • 80

    The agglutination test was performed with dilutions of serum 1:50; 1:100; 1:200; 1:400; 1:800. When evaluating the results in all dilutions, as well as in the control, a positive reaction was observed. What is the titer of the agglutination reaction?

    the reaction is set incorrectly

  • 81

    The agglutination reaction was performed with serum dilutions in ratios of 1:50; 1:100; 1:200; 1:400; 1:800. When evaluating the results, a positive reaction was observed in dilutions of 1:50; 1:100; 1:200; 1:400. In test tubes with dilutions of 1:800 and in the control, agglutination was not observed. Serum agglutinating titer:

    1:400

  • 82

    Diagnostic titer of agglutinating serum:

    titer confirming the disease

  • 83

    An agglutination reaction in which erythrocytes with antigens adsorbed on them are used as a diagnosticum is called:

    indirect hemagglutination reaction

  • 84

    In an indirect hemagglutination reaction, the following is used as a diagnosticum:

    erythrocytes with antigens adsorbed on them

  • 85

    Hemagglutination inhibition reaction is used for:

    virus identification

  • 86

    The Coombs reaction is used for:

    detection of incomplete antibodies detection of antibodies

  • 87

    Used to detect incomplete antibodies:

    Coombs reaction

  • 88

    Anti-human (antiglobulin) antibodies are used in:

    Coombs reactions

  • 89

    Precipitation reaction is determined by:

    the appearance of turbidity

  • 90

    The directed movement of leukocytes up a gradient concentration toward the site of infection. This movement is

    Chemotaxis

  • 91

    The agglutination reaction is manifested by:

    with the formation of sediment

  • 92

    The inhibation of hemagglutination reaction is used:

    in the identification of viruses

  • 93

    Enzyme-Linked Immunosorbent Assay is based on:

    detection of the corresponding antigen with the help of antibodies labeled with enzymes