記憶度
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問題一覧
1
How many human cells comprise your body
3x10^13
2
How many microbiota cells do you carry?
3 x 10^14
3
How many different microbial habitats does your body have?
At least 100, probably more
4
Skin Area = 2sq meters. Mucous membrane area = ___ sq m
200x = 400cm^2
5
The skin reaction (rash) as a result of a tick bite is known as
Bull’s eye rash
6
This rash is a sign of what infectious disease?
Lyme disease
7
If you have a dangerous, contagious, infectious disease you should be
isolated
8
What components serve as adhesion? (Select all that apply)
pili , capsules , surface glycoproteins , surface polysaccharide , hemagglutinins
9
Phagocytes are what type of body cell?
most numerous white blood cell
10
What does the body use for iron (select all that apply)
hemoglobins , catalase enzyme , cytochromes , myoglobin
11
The most abundant WBC (leukocyte) in normal blood is the
neutrophil
12
A normal WBC count in blood is (select all that apply)
5000-10,000/ul , 5-10million/ul , 25-50 billion per person
13
What happens to the neutrophil count during bacterial infection
numbers go way up and activity increase
14
What happens to the neutrophil count during viral infection
numbers go down way below normal
15
How are therapeutic amounts of interferon obtained?
extracted from Chinese-hamster ovary cell culture
16
Why isn’t interferon used therapeutically to prevent cold and flu illnesses
treatment can make you feel very sick
17
The human body is extremely sensitive to anything bacterial and viral. We know this because
you’re Immune system strengthens just by hearing about someone you know has mono
18
When in development does ‘clonal deletion’ of B cells happen
Within a few weeks of birth
19
One plasma cell can synthesize more than _____ antibody molecules per hour
15 million
20
How many different antigens is your immune system prepared to react in your life time?
100 million
21
How does IgE cause allergy symptoms?
causes toxic levels of histamine to be released from basophiles and mast cells
22
What pathogenic microbe specifically targets CD4+ helper T-cells and destroys them—leading to serious diseases
HIV
23
The “booster” shot that is given a month or 2 after vaccination is meant to
stimulate a secondary response to the vaccine antigen
24
The symbiotic relationship in commensalism is best described as:
one partner benefits the other one doesn’t benefit and isn’t harmed
25
Symbiotic realtionship is parasitism is best described as:
one benefits at the expense (harm) of the other
26
The symbiotic relationship mutualism is best described as
both dervive some benefit from being together
27
Quarantine is best described as
when a well person that has been exposed to a contagious disease is separated from others for a specific period of time
28
Isolation is best described as
when a sick person with infectious disease symptoms is separated from other people
29
Infectious (disease) is best described
disease symptoms caused by growth of microorganism on or in the body
30
Contagious is best described as
specific diseases that can be spread from person to person
31
What best describes the difference between bacteremia and septicemia?
in septicemia the pathogen is actively growing in the blood; in bacteremia the blood is just transporting bacteria that growing elsewhere
32
What type of illnesses did Tom get while in the hospital for surgery?
surgical wound infection in his knee
33
What species caused his infection?
nosocomial strain of antibiotic resistant staphylococcus
34
The pathogenic species that caused Tom’s infection had to be somehow transmitted from its reservoir. Most likely in a hospital setting the reservoir for this particular species is
common surfaces that are frequently touched by others
35
MRSA strains that cause surgical wound infections are particularly dangerous in joints such as knee because
they are resistant to many of the common antibiotics and are not easily cured. leading to further complication
36
For joint infectious the standard treatment for this pathogen is
surgically opening the wound, cleaning it out, then using antibiotics
37
For Tom’s strain of MRSA what was the antibiotic of choice and how was it most likely administered to Tom
vancomycin, metered IV drip over 6 weeks
38
The outcome of Tom’s encounter with this one bacterial species in the hospital was
he recovered completely helped the Patriots win 3 more Super Bowl then moved to Tampa bay and won another
39
Which term represents number of past cases of diseases during a specific period of time e.g(all of) 2023
incidence
40
Which terms represent the current number of cases of the diseases
prevalence
41
Does “flattening the curve” refer to reducing covid-19’s prevalence or incidence
prevalence
42
What effect would flattening the curve of a disease like COVID-19 have on the incidence of the disease (in the absence of an effective vaccine)
incidence may stay the nearly the same, but spread out over a longer period of time
43
Considering a disease like COVID-19; what is better—an absolute 1-pill cure or an effective vaccine
effective vaccine prevents the diseases from ever happening no need for a pill
44
Immunoglobulin molecules as best described as
glycoproteins with 4 peptides arranged in a basic Y shape
45
The paratrooper of an immunoglobulin is the
the site on the antibody molecule that bind to the epitope of the antigen
46
Optimization refers to
enhancing phagocytosis
47
Neutralization is an immune component interaction that inactives what?
viruses,toxins,and bacterial pathogens
48
Natural killers cells, macrophages, and eosinophile are cytoxic meaning they can
kill virus infected cells and large pathogens
49
The immunoglobin (Ig) with a valence of 10 is
IgM
50
The Ig that can be secreted into mucus, saliva, tears etc is
IgA
51
The portion of the adaptive immune system that produces the soluble, circulating version of immune protection
humoral
52
Which type of cell is the lg factory, i.e. the one that produces the immunoglobulin
B Plasma cell
53
What best describes a substance known as an antigen
foreign, large molecule, immunogenic
54
How do specific anti-toxin antibodies “neutralized” toxins produce by bacteria to make them non-toxic to the body
they bind to the toxin preventing it from interacting with and damaging the target cell
55
In the antibody-antigen reaction known as “antibody-dependent cell mediated cytotoxicity (ADCC)” what is the main “effector cell” that secretes the cytoxin that kills the pathogenic bacteria?
natural killer cells
56
The clinical procedure for collecting sample for an antibody tiger for the SARS-CoV2 virus is
taking blood sample
57
The antibody test for the virus detects what immunoglobulin?
both IgM and IgG
58
How soon after Covid infection starts circulating antibodies be detected
5-6 days
59
What part of the coronavirus is most likely immunogenic and would stimulate active immunity against the virus?
the protein spikes sticking out from the envelope
60
How long does natural immunity last against the virus?
we don’t know-this is a new historical data to say for sure
61
What possible forms could an effective vaccine material be in to stimulate protective antibody level agasint any type of virus
any of these could be potential vaccine components
62
Serological test for antibody level in the population are important in a pandemic because
it may tell us the level of herd immunity in the population, important for return to work returning
63
In our free society in the US, could anyone actually required to get vaccinated against this cornovrius
yes rules can be made at the state and local level requiring people be vaccinated agasint specific disease, espically health care workers
64
What is a cytokine?
a chemical mediator (stimulus) of inflammation that is released by cells in response to tissue or cell damage
65
Cardiac diseases is considered a(n)_____ (acute, or chronic) diseases with a CRP level greater than ____ mg/L indicating high risk
chronic 3
66
Where is CRP produced in the body?
in the liver
67
In what line of defense in C-reactive protein (CRP) considered a signficant component?
second line—innate immunity
68
Many of the conditions that stimulate CRP production do so by raising the level of the cytokine ______
interleukin 6
69
CRP is produced In response to what? (Choose all that apply)
inflammation due to bacterial infection , inflammation due to viral infection , malignant cancers , tissues injury , diabetes