問題一覧
1
is the 4th and final stage of aerobic respiration.
krebs cycle
2
Krebs cycle also known as
citric acid cycle,tricarboxylic cycle
3
Krebs cycle is a process to generate more high energy molecules like ___,___,___?
nadh,fadh2,atp
4
Krebs produce additional co2 molecules known as
by products
5
Krebs 1st Process:
amphibolic
6
Krebs 2nd Process
oxidative catabolism of carbs fa,aa
7
Krebs 1.Energy products
gtp(atp)
8
Krebs 2.Energy products
nadh,fadh2
9
Krebs Location
mitochondria
10
Krebs O2 requirement
aerobic
11
Krebs Overall rxn.
acetyl coa+3nad++fad+gdp+pi~2co2+coa-sh+3nadh+h++fadh2+gtp
12
1.Condensation-formation: Process:
aldol condensation followed by hydrolysis
13
1.Condensation formation Key enzyme:
citrate synthase
14
First irreversible step/ regulatory step
condensation formation
15
2.Dehydration and Hydration Process:
Isomerization via cis=aconitase; interchange of –H and -OH
16
2.Dehydration and hydration Key enzyme:
aconitase
17
2.Dehydration and hydration Function:
activate decarboxylation
18
3.Oxidative decarboxylation Process:
oxidative decarboxylation/"C" is removed as CO2, NAD+ reduced to NADH
19
3.Oxidative decarboxylation Key enzyme:
isocitrate dehydrogenase
20
2nd irreversible step
oxidative decarboxylation
21
4. Oxidative decarboxylation Process:
Oxidative decarboxylation; C removed as CO2; NAD+ reduced to NADH and thioester formation
22
4. Oxidative decarboxylation Key enzyme:
a ketoglutarate dh requires TTP, lipoamide, FAD
23
3rd irreversible step
oxidative decarboxylation
24
5.Substrate level phosphorylation Process:
Phosphorylation where thioester energy of thioester conserved in phosphoanhydride bond of GTP/ATP
25
5.Substrate level phosphorylation Key enzyme:
succinyl coa synthetase
26
6.Dehydrogenation Process:
Double bond formation; FAD reduced to FADH2
27
6.Dehydrogenation Key enzyme:
succinate dh
28
7.Hydration Process:
addition of h2o to introduced to -OH
29
7.Hydration Key enzyme:
fumarase
30
7.Hydration Function:
preparation for the next oxidation step
31
8.Dehydrogenation Process:
Oxidation; NAD+ reduced to NADH
32
8.Dehydrogenation Key enzyme:
malate dh