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1
Operates at the end of the chromosome this is an enzyme consisting of a protein and an rna component which the rna serves as a template for synthesizing telomere dna
TELOMERASE
2
Replication of faculty petrochromatin occurs during the late what stage of the cell cycle
S STAGE
3
Ensures correct progression before leading to phases of cell cycle
PROTEIN
4
Reduce levels of this regulatory protein for outcome for breast cancer patients
p27
5
What are the different classifications of centromere based on its position
METACENTRIC, ACROCENTRIC, SUBMETACENTRIC
6
Classification of centrome which centromere is position is between near one end of the q arm
ACROCENTRIC
7
Chromosomes are joined together by which allow proper separation during mitosis and meiosis
CENTROMERE
8
What are the two types of chromatin
EUCHROMATIN, HETEROCHROMATIN
9
Cell cycle regulator which controls the g1 to s phase and also prepare dna replication
CdK 4-G1 CdK
10
It is the physical end of chromosomes which acts as protective cups of chromosome ends and it prevents end to end fusion of chromosomes
TELOMERE
11
Chromosomes are composed of
NUCLEOPROTEIN
12
How many pairs of non sex chromosomes do human have
22
13
This holds sister chromatid destroyed by the APC/C
COHESIN
14
What are the different stages of mitosis
PROPHASE, METAPHASE, ANAPHASE, TELOPHASE
15
It is an specific chromosomal region found in the satellite stalks of human acrocentric chromosome
NUCLEOLAR ORGANIZING REGION
16
Condensation of facultative heterochromatin occurs during
INTERPHASE
17
What are the two types of heterochromatin
FACULTATIVE, CONSTITUTIVE
18
What are the stages of the cell cycle
GAP 1, SYNTHESIS, GAP 2, MITOSIS
19
It is also known as cyclosome which destroys Cohesin allowing sister chromatids to separate and degrades mitotic cyclins
ANAPHASE PROMOTING COMPLEX
20
Classification of centromere which the centrome is located in the middle ensures that chromosomes from the p and q arm are equally divided
METACENTRIC
21
G1 cyclins activates what CdK in preparation of DNA replication
4, 6
22
This refers to cytoplasmic division
CYTOKINESIS
23
Process of cell cycle which halving of the genome
MITOSIS PHASE
24
This refers to the production of similar genes of offspring from the parent cell
REPLICATION
25
What are the two alternating processes of the cell cycle
S PHASE, M PHASE
26
This chromosomes determines the biological sex
SEX CHROMOSOME
27
Serves as the attachment site for kinetochore
CENTROMERE
28
Constitutive heterochromatin are commonly found on
CENTROMERE, TELOMERE
29
This is a result of dna degradation or chromosome breakage due to collision
END TO END FUSION
30
A constriction visible on metaphase chromosomes where two sister chromatids are joined together. It is essential to the survival of the chromosome during cell division.
CENTROMERE
31
Also known as D cyclin
G1 CYCLIN
32
This is the stage of cell cycle which the nuclear division or the chromosome separates in identical sets and the cytoplasmic division which is the cytokinesis occurs
MITOSIS
33
Tumor suppressor protein which functions to block the cell cycle if the dna is damaged and it can also lead to apoptosis when the dna damage is severe.
p53
34
How many pairs of sex chromosomes do human have
1
35
Type of chromatin which is highly contracted genetically inactive and late replicating during the space of mitosis which is does not participate in gene expression
HETEROCHROMATIN
36
This refers to the condition where the extreme case of p53 mutation leads to high frequency of cancer in affected individuals
LI FRAUMENI SYNDROME
37
A disease that results when the regulation of the cell cycle is not controlled and normal cell growth and behavior is lost
CANCER
38
This refers to the pairing of homologous chromosome
SYNAPSIS
39
A ordered set of events resulting in cell growth and division into two daughter cells
CELL CYCLE
40
How many chromosomes are are found in one copy of acrocentric chromose of humans
5
41
Stage of cell cycle which is the final preparation of mitosis
GAP 2
42
Stage of cell cycle which is the growth and preparation of the chromosomes for replication in which the cell also experiences growth and prepares for dna replication. This also produce rna and proteins
GAP 1
43
Group is added to a variety of protein substrate that control processes into the cell cycle
PHOSPHATE
44
Cell cycle regulator ensures that there is accurate separation of chromosomes in the cell division
CdK 1-M PHASE CdK
45
What is the chromosome for female
XX
46
These are non sex chromosomes that carries genetic information related to the body traits and function
AUTOSOME
47
Inactivated x chromosome of female cells are also known as
BARR BODY
48
Cell regulator which levels remain fairly stable but each must bind with the appropriate cycling in order to be activated
CYCLIN DEPENDENT KINASE
49
Chromosome is the site where interaction with the____during cell division
MITOTIC SPINDLE
50
What is the chromosome for males
XY
51
A cell cycle inhibitor which blocks the entry in the space by binding to cyclins and CdK
p27
52
These are the structure of chromosome which contains the dna which packages the nuclear genetic material of the cell
NUCLEOPROTEIN
53
This refers to dna forming rna to protein
TRANSCRIPTION
54
This contains the tightly called double helix structure of dna
SISTER CHROMATID
55
What is the general role of ribosome
PROTEIN SYNTHESIS
56
Cell cycle regulator which regulates s phase and ensures dna duplication
CdK2-S PHASE CdK
57
A process of cell cycle which is the doubling of its genome which doubles DNA
SYNTHESIS PHASE
58
Regulatory proteins that find to cdk which levels rise and fall with the stages of cell cycle
CYCLIN
59
This prevents dna degradation resulting after chromosome breakage and it plays a role in synapsis during meiosis
TELOMERE
60
A protein context which that allows the attachment and alignment of the mitotic spindle fibers
KINETOCHORE
61
Type of Heterochromatin which is the condensed inactivated x chromosome of female cells in which one x chromosome of every female cell is randomly inactivated
FACULTATIVE
62
What phase do centromere is visible at
METAPHASE
63
This ensures chromosome stability and proper cell segregation during cell division
CENTROMERE
64
This occurs during cytokinesis
CLEAVAGE FURROW, CELL PLATE
65
This is the stage when the dna replication occurs and the duplication of the centrosome
SYNTHESIS
66
How many pairs of chromosomes in somatic cells do human have
23
67
Also known as Mitotic cyclin
B
68
The type of a heterochromatin is able to switch to active to inactive chromatin depending on the cell type and development
FACULTATIVE
69
Type of heterochromatin which consists of simple repeats of nitrogenous bases responsible for the regulation of crossing over the exchange of genes from one sister chromatid to the other during cell division
CONSTITUTIVE
70
Also known as S phase cyclin
E, A
71
What chromosomes do acrocentric chromosome of nuclear organizing region found
13, 14, 15, 22
72
This is the functional elements microtubules that separate the sister chromatids during cell division
MITOTIC SPINDLE
73
This attach to chromosomes to the spinal fibers during cell division
KINETOCHORE APPARATUS
74
Is the structure that is found in the nucleus and where genes are located
CHROMOSOME
75
Type of chromatin which is loosely organized extended and uncoiled which is applicable for transcription. It contains active early replicating genes for gene expression during S phase of cell cycle
EUCHROMATIN
76
How many nor human chromosome have
10
77
It is responsible for the formation of nucleoli during interphase cell cycle also serves as the site of rrna genes and its production
NUCLEOLAR ORGANIZING REGION
78
They play crucial role for the accurate distribution of genetic information to the daughter cells.
CHROMOSOME
79
How many sister chromatids contains in one chromosome
2
80
Mutation of this cell cycle regulator is the most frequent mutation leading to cancer
p53
81
Classification of centromere which found at the end or slightly of the center between middle and end resulting to one arm longer
SUBMETACENTRIC