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1
Is the structure that is found in the nucleus and where genes are located
CHROMOSOME
2
Chromosomes are composed of
NUCLEOPROTEIN
3
These are the structure of chromosome which contains the dna which packages the nuclear genetic material of the cell
NUCLEOPROTEIN
4
They play crucial role for the accurate distribution of genetic information to the daughter cells.
CHROMOSOME
5
How many sister chromatids contains in one chromosome
2
6
This contains the tightly called double helix structure of dna
SISTER CHROMATID
7
Chromosomes are joined together by which allow proper separation during mitosis and meiosis
CENTROMERE
8
How many pairs of chromosomes in somatic cells do human have
23
9
These are non sex chromosomes that carries genetic information related to the body traits and function
AUTOSOME
10
This chromosomes determines the biological sex
SEX CHROMOSOME
11
What is the chromosome for female
XX
12
What is the chromosome for males
XY
13
How many pairs of non sex chromosomes do human have
22
14
How many pairs of sex chromosomes do human have
1
15
What phase do centromere is visible at
METAPHASE
16
A constriction visible on metaphase chromosomes where two sister chromatids are joined together. It is essential to the survival of the chromosome during cell division.
CENTROMERE
17
Chromosome is the site where interaction with the____during cell division
MITOTIC SPINDLE
18
This ensures chromosome stability and proper cell segregation during cell division
CENTROMERE
19
Serves as the attachment site for kinetochore
CENTROMERE
20
A protein context which that allows the attachment and alignment of the mitotic spindle fibers
KINETOCHORE
21
This is the functional elements microtubules that separate the sister chromatids during cell division
MITOTIC SPINDLE
22
This attach to chromosomes to the spinal fibers during cell division
KINETOCHORE APPARATUS
23
What are the different classifications of centromere based on its position
METACENTRIC, ACROCENTRIC, SUBMETACENTRIC
24
Classification of centromere which the centrome is located in the middle ensures that chromosomes from the p and q arm are equally divided
METACENTRIC
25
Classification of centrome which centromere is position is between near one end of the q arm
ACROCENTRIC
26
Classification of centromere which found at the end or slightly of the center between middle and end resulting to one arm longer
SUBMETACENTRIC
27
It is the physical end of chromosomes which acts as protective cups of chromosome ends and it prevents end to end fusion of chromosomes
TELOMERE
28
This prevents dna degradation resulting after chromosome breakage and it plays a role in synapsis during meiosis
TELOMERE
29
This is a result of dna degradation or chromosome breakage due to collision
END TO END FUSION
30
This refers to the production of similar genes of offspring from the parent cell
REPLICATION
31
This refers to the pairing of homologous chromosome
SYNAPSIS
32
Operates at the end of the chromosome this is an enzyme consisting of a protein and an rna component which the rna serves as a template for synthesizing telomere dna
TELOMERASE
33
It is an specific chromosomal region found in the satellite stalks of human acrocentric chromosome
NUCLEOLAR ORGANIZING REGION
34
What chromosomes do acrocentric chromosome of nuclear organizing region found
13, 14, 15, 22
35
It is responsible for the formation of nucleoli during interphase cell cycle also serves as the site of rrna genes and its production
NUCLEOLAR ORGANIZING REGION
36
What is the general role of ribosome
PROTEIN SYNTHESIS
37
How many chromosomes are are found in one copy of acrocentric chromose of humans
5
38
How many nor human chromosome have
10
39
What are the two types of chromatin
EUCHROMATIN, HETEROCHROMATIN
40
Type of chromatin which is loosely organized extended and uncoiled which is applicable for transcription. It contains active early replicating genes for gene expression during S phase of cell cycle
EUCHROMATIN
41
This refers to dna forming rna to protein
TRANSCRIPTION
42
Type of chromatin which is highly contracted genetically inactive and late replicating during the space of mitosis which is does not participate in gene expression
HETEROCHROMATIN
43
What are the two types of heterochromatin
FACULTATIVE, CONSTITUTIVE
44
The type of a heterochromatin is able to switch to active to inactive chromatin depending on the cell type and development
FACULTATIVE
45
Inactivated x chromosome of female cells are also known as
BARR BODY
46
Condensation of facultative heterochromatin occurs during
INTERPHASE
47
Replication of faculty petrochromatin occurs during the late what stage of the cell cycle
S STAGE
48
Type of Heterochromatin which is the condensed inactivated x chromosome of female cells in which one x chromosome of every female cell is randomly inactivated
FACULTATIVE
49
Type of heterochromatin which consists of simple repeats of nitrogenous bases responsible for the regulation of crossing over the exchange of genes from one sister chromatid to the other during cell division
CONSTITUTIVE
50
Constitutive heterochromatin are commonly found on
CENTROMERE, TELOMERE
51
A ordered set of events resulting in cell growth and division into two daughter cells
CELL CYCLE
52
What are the two alternating processes of the cell cycle
S PHASE, M PHASE
53
A process of cell cycle which is the doubling of its genome which doubles DNA
SYNTHESIS PHASE
54
Process of cell cycle which halving of the genome
MITOSIS PHASE
55
This refers to cytoplasmic division
CYTOKINESIS
56
What are the stages of the cell cycle
GAP 1, SYNTHESIS, GAP 2, MITOSIS
57
Stage of cell cycle which is the growth and preparation of the chromosomes for replication in which the cell also experiences growth and prepares for dna replication. This also produce rna and proteins
GAP 1
58
This is the stage when the dna replication occurs and the duplication of the centrosome
SYNTHESIS
59
Stage of cell cycle which is the final preparation of mitosis
GAP 2
60
This is the stage of cell cycle which the nuclear division or the chromosome separates in identical sets and the cytoplasmic division which is the cytokinesis occurs
MITOSIS
61
What are the different stages of mitosis
PROPHASE, METAPHASE, ANAPHASE, TELOPHASE
62
This occurs during cytokinesis
CLEAVAGE FURROW, CELL PLATE
63
Ensures correct progression before leading to phases of cell cycle
PROTEIN
64
Cell regulator which levels remain fairly stable but each must bind with the appropriate cycling in order to be activated
CYCLIN DEPENDENT KINASE
65
Group is added to a variety of protein substrate that control processes into the cell cycle
PHOSPHATE
66
Cell cycle regulator which controls the g1 to s phase and also prepare dna replication
CdK 4-G1 CdK
67
Cell cycle regulator which regulates s phase and ensures dna duplication
CdK2-S PHASE CdK
68
Cell cycle regulator ensures that there is accurate separation of chromosomes in the cell division
CdK 1-M PHASE CdK
69
Regulatory proteins that find to cdk which levels rise and fall with the stages of cell cycle
CYCLIN
70
G1 cyclins activates what CdK in preparation of DNA replication
4, 6
71
Also known as D cyclin
G1 CYCLIN
72
Also known as S phase cyclin
E, A
73
Also known as Mitotic cyclin
B
74
It is also known as cyclosome which destroys Cohesin allowing sister chromatids to separate and degrades mitotic cyclins
ANAPHASE PROMOTING COMPLEX
75
This holds sister chromatid destroyed by the APC/C
COHESIN
76
Tumor suppressor protein which functions to block the cell cycle if the dna is damaged and it can also lead to apoptosis when the dna damage is severe.
p53
77
Mutation of this cell cycle regulator is the most frequent mutation leading to cancer
p53
78
This refers to the condition where the extreme case of p53 mutation leads to high frequency of cancer in affected individuals
LI FRAUMENI SYNDROME
79
A disease that results when the regulation of the cell cycle is not controlled and normal cell growth and behavior is lost
CANCER
80
A cell cycle inhibitor which blocks the entry in the space by binding to cyclins and CdK
p27
81
Reduce levels of this regulatory protein for outcome for breast cancer patients
p27