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CHROMOSOME STRUCTURE
  • Jef Marc Valencia

  • 問題数 81 • 2/5/2025

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    問題一覧

  • 1

    Is the structure that is found in the nucleus and where genes are located

    CHROMOSOME

  • 2

    Chromosomes are composed of

    NUCLEOPROTEIN

  • 3

    These are the structure of chromosome which contains the dna which packages the nuclear genetic material of the cell

    NUCLEOPROTEIN

  • 4

    They play crucial role for the accurate distribution of genetic information to the daughter cells.

    CHROMOSOME

  • 5

    How many sister chromatids contains in one chromosome

    2

  • 6

    This contains the tightly called double helix structure of dna

    SISTER CHROMATID

  • 7

    Chromosomes are joined together by which allow proper separation during mitosis and meiosis

    CENTROMERE

  • 8

    How many pairs of chromosomes in somatic cells do human have

    23

  • 9

    These are non sex chromosomes that carries genetic information related to the body traits and function

    AUTOSOME

  • 10

    This chromosomes determines the biological sex

    SEX CHROMOSOME

  • 11

    What is the chromosome for female

    XX

  • 12

    What is the chromosome for males

    XY

  • 13

    How many pairs of non sex chromosomes do human have

    22

  • 14

    How many pairs of sex chromosomes do human have

    1

  • 15

    What phase do centromere is visible at

    METAPHASE

  • 16

    A constriction visible on metaphase chromosomes where two sister chromatids are joined together. It is essential to the survival of the chromosome during cell division.

    CENTROMERE

  • 17

    Chromosome is the site where interaction with the____during cell division

    MITOTIC SPINDLE

  • 18

    This ensures chromosome stability and proper cell segregation during cell division

    CENTROMERE

  • 19

    Serves as the attachment site for kinetochore

    CENTROMERE

  • 20

    A protein context which that allows the attachment and alignment of the mitotic spindle fibers

    KINETOCHORE

  • 21

    This is the functional elements microtubules that separate the sister chromatids during cell division

    MITOTIC SPINDLE

  • 22

    This attach to chromosomes to the spinal fibers during cell division

    KINETOCHORE APPARATUS

  • 23

    What are the different classifications of centromere based on its position

    METACENTRIC, ACROCENTRIC, SUBMETACENTRIC

  • 24

    Classification of centromere which the centrome is located in the middle ensures that chromosomes from the p and q arm are equally divided

    METACENTRIC

  • 25

    Classification of centrome which centromere is position is between near one end of the q arm

    ACROCENTRIC

  • 26

    Classification of centromere which found at the end or slightly of the center between middle and end resulting to one arm longer

    SUBMETACENTRIC

  • 27

    It is the physical end of chromosomes which acts as protective cups of chromosome ends and it prevents end to end fusion of chromosomes

    TELOMERE

  • 28

    This prevents dna degradation resulting after chromosome breakage and it plays a role in synapsis during meiosis

    TELOMERE

  • 29

    This is a result of dna degradation or chromosome breakage due to collision

    END TO END FUSION

  • 30

    This refers to the production of similar genes of offspring from the parent cell

    REPLICATION

  • 31

    This refers to the pairing of homologous chromosome

    SYNAPSIS

  • 32

    Operates at the end of the chromosome this is an enzyme consisting of a protein and an rna component which the rna serves as a template for synthesizing telomere dna

    TELOMERASE

  • 33

    It is an specific chromosomal region found in the satellite stalks of human acrocentric chromosome

    NUCLEOLAR ORGANIZING REGION

  • 34

    What chromosomes do acrocentric chromosome of nuclear organizing region found

    13, 14, 15, 22

  • 35

    It is responsible for the formation of nucleoli during interphase cell cycle also serves as the site of rrna genes and its production

    NUCLEOLAR ORGANIZING REGION

  • 36

    What is the general role of ribosome

    PROTEIN SYNTHESIS

  • 37

    How many chromosomes are are found in one copy of acrocentric chromose of humans

    5

  • 38

    How many nor human chromosome have

    10

  • 39

    What are the two types of chromatin

    EUCHROMATIN, HETEROCHROMATIN

  • 40

    Type of chromatin which is loosely organized extended and uncoiled which is applicable for transcription. It contains active early replicating genes for gene expression during S phase of cell cycle

    EUCHROMATIN

  • 41

    This refers to dna forming rna to protein

    TRANSCRIPTION

  • 42

    Type of chromatin which is highly contracted genetically inactive and late replicating during the space of mitosis which is does not participate in gene expression

    HETEROCHROMATIN

  • 43

    What are the two types of heterochromatin

    FACULTATIVE, CONSTITUTIVE

  • 44

    The type of a heterochromatin is able to switch to active to inactive chromatin depending on the cell type and development

    FACULTATIVE

  • 45

    Inactivated x chromosome of female cells are also known as

    BARR BODY

  • 46

    Condensation of facultative heterochromatin occurs during

    INTERPHASE

  • 47

    Replication of faculty petrochromatin occurs during the late what stage of the cell cycle

    S STAGE

  • 48

    Type of Heterochromatin which is the condensed inactivated x chromosome of female cells in which one x chromosome of every female cell is randomly inactivated

    FACULTATIVE

  • 49

    Type of heterochromatin which consists of simple repeats of nitrogenous bases responsible for the regulation of crossing over the exchange of genes from one sister chromatid to the other during cell division

    CONSTITUTIVE

  • 50

    Constitutive heterochromatin are commonly found on

    CENTROMERE, TELOMERE

  • 51

    A ordered set of events resulting in cell growth and division into two daughter cells

    CELL CYCLE

  • 52

    What are the two alternating processes of the cell cycle

    S PHASE, M PHASE

  • 53

    A process of cell cycle which is the doubling of its genome which doubles DNA

    SYNTHESIS PHASE

  • 54

    Process of cell cycle which halving of the genome

    MITOSIS PHASE

  • 55

    This refers to cytoplasmic division

    CYTOKINESIS

  • 56

    What are the stages of the cell cycle

    GAP 1, SYNTHESIS, GAP 2, MITOSIS

  • 57

    Stage of cell cycle which is the growth and preparation of the chromosomes for replication in which the cell also experiences growth and prepares for dna replication. This also produce rna and proteins

    GAP 1

  • 58

    This is the stage when the dna replication occurs and the duplication of the centrosome

    SYNTHESIS

  • 59

    Stage of cell cycle which is the final preparation of mitosis

    GAP 2

  • 60

    This is the stage of cell cycle which the nuclear division or the chromosome separates in identical sets and the cytoplasmic division which is the cytokinesis occurs

    MITOSIS

  • 61

    What are the different stages of mitosis

    PROPHASE, METAPHASE, ANAPHASE, TELOPHASE

  • 62

    This occurs during cytokinesis

    CLEAVAGE FURROW, CELL PLATE

  • 63

    Ensures correct progression before leading to phases of cell cycle

    PROTEIN

  • 64

    Cell regulator which levels remain fairly stable but each must bind with the appropriate cycling in order to be activated

    CYCLIN DEPENDENT KINASE

  • 65

    Group is added to a variety of protein substrate that control processes into the cell cycle

    PHOSPHATE

  • 66

    Cell cycle regulator which controls the g1 to s phase and also prepare dna replication

    CdK 4-G1 CdK

  • 67

    Cell cycle regulator which regulates s phase and ensures dna duplication

    CdK2-S PHASE CdK

  • 68

    Cell cycle regulator ensures that there is accurate separation of chromosomes in the cell division

    CdK 1-M PHASE CdK

  • 69

    Regulatory proteins that find to cdk which levels rise and fall with the stages of cell cycle

    CYCLIN

  • 70

    G1 cyclins activates what CdK in preparation of DNA replication

    4, 6

  • 71

    Also known as D cyclin

    G1 CYCLIN

  • 72

    Also known as S phase cyclin

    E, A

  • 73

    Also known as Mitotic cyclin

    B

  • 74

    It is also known as cyclosome which destroys Cohesin allowing sister chromatids to separate and degrades mitotic cyclins

    ANAPHASE PROMOTING COMPLEX

  • 75

    This holds sister chromatid destroyed by the APC/C

    COHESIN

  • 76

    Tumor suppressor protein which functions to block the cell cycle if the dna is damaged and it can also lead to apoptosis when the dna damage is severe.

    p53

  • 77

    Mutation of this cell cycle regulator is the most frequent mutation leading to cancer

    p53

  • 78

    This refers to the condition where the extreme case of p53 mutation leads to high frequency of cancer in affected individuals

    LI FRAUMENI SYNDROME

  • 79

    A disease that results when the regulation of the cell cycle is not controlled and normal cell growth and behavior is lost

    CANCER

  • 80

    A cell cycle inhibitor which blocks the entry in the space by binding to cyclins and CdK

    p27

  • 81

    Reduce levels of this regulatory protein for outcome for breast cancer patients

    p27