問題一覧
1
classification of tumors
carcinoma, sarcoma, lymphomas and leukemias, nervous tissue tumors, myeloma
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Situated in the nucleus is the genetic material or
DNA
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The process by which cells grow and divide to replenish lost cells
cell proliferation
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Phase includes growth and prep of chromosomes for replication.
gap 1
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fat
lipo
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is made up of subunits called genes
DNA
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is a common health problem worldwide
cancer
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cartilage
chrondo
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_____ and _____act by damaging genes, viruses introduce their own genes into cells, and _____ passes on alterations in genes that make a person more susceptible to cancer
chemicals and radiation, heredity
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bone marrow
myelo
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red blood cell
erythro
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is one of four epidemic non-communicable diseases (NCDs) or lifestyle-related illnesses (LRDs)
cancer
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common lymphoma
lymph nodes
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gland
adeno
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common carcinomas
lung, breast, colon, bladder prostate
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The process by which normal, healthy cells transform into cancer cells.
carcinogenesis
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resting stage, when a cell leaves the cell cycle, either temporarily or permanently. Often, they will never reenter the cell but instead will carry out their function in the organism until they die.
gap 0
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proliferative patterns of cells
hyperplasia, dysplasia, metaplasia, anaplasia, neoplasia
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An increase in the number of new cells in an organ or tissue It causes the affected tissue or organ to enlarge.
hyperplasia
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Phase includes preparation for mitosis.
gap 2
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Tumor growth may be promoted by disturbances in hormonal balance, either by the body’s own (endogenous) hormone production or by administration of exogenous hormones.
hormonal agents
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Some important genes in the context of cellular proliferation include:
proto-oncogenes, tumor supressor genes
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the replication of genetic material and cell division are all governed by the cell cycle
cell growth
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lymphocyte
lympho
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is a malignant tumor of blood vessels located in the skin. This type of cancer is not directly caused by HIV infectin
kaposi’s sarcoma
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Associated with an increased risk of breast cancer
✔ Early onset of menses before age 12 ✔ Delayed onset of menopause after age 55, ✔ nulliparity (never giving birth), ✔ delayed childbirth after age 30
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pigment cell
melano
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The mechanism for regulating the removal of excess and impaired cells. Also referred to as cell suicide or programmed cell death. Is an orderly process during which internal cellular structures are progressively dismantled, the impaired cell shrinks and finally is rapidly destroyed by immune cells
apoptosis
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Viral infections that increase risk of certain forms of cancer
human papilloma virus(cervial cancer), epstein-barr virus(lymphoma and nasopharyngeal cancer, hep b and c(hepatocelluar cancer)
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The most common cancers are in the
lungs, breast, colon, rectum, and prostate.
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Phase is where DNA replication occurs.
synthesis
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Cancer is one of four epidemic non-communicable diseases (NCDs) or lifestyle-related illnesses (LRDs), which include
CVD, type 2 diabetes, chronic respiratory disease
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examples of chemical agents
❑ Vinyl Chloride (used for plastic manufacture, asbestos factories, construction works) ❑ Polycyclic aromatic hydrocarbons (such as from refuse burning, auto and truck emissions, oil refineries, air pollution) ❑Arsenic, soot and tars ❑ Fertilizers, weed killers (pesticides) ❑ formaldehydes
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The leading causes of cancer-related death in the United States in order of frequency and location in women
lung, breast, and colorectal cancer
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a type of gene that makes a protein called a tumour suppressor protein that helps control cell growth.
tumor supressor genes
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is one bacterium identified as a cause of cancer in humans – associated with incidence of gastric malignancy related to chronic superficial gastritis with resultant metaplastic changes to the gastric mucosa
helicobater pylori
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Means new growth but not the good kind. It is the abnormal and uncontrolled proliferation of cells or tissues in the body. Can be benign or malignant, depending on whether it stays localized or invades and spreads to other organs
neoplasia
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Progression through the cell cycle depends on successful passage through a number of critical phases
checkpoints
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liver
hepato
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gene involved in normal cell growth.
proto-oncogenes
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muscle
myo
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a highly-ordered series of events that culminates in mitosis
cell cycle
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common leukemia
bloodstream
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blood vessels
hemangio
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Examples of gene related cancer
Retinoblastoma, pheochromocytoma, Wilm’s tumor, lung cancer, breast cancer
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cause vaginal carcinomas
DIETHYLSTILBESTROL
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is a term used to describe cells that have lost the unique characteristics that define them as a certain tissue type
anaplasia
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Is a condition where cells grow abnormally in size, shape or organization and may become cancerous overtime.
dysplasia
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fundamental building block for life.
DNA
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are now regarded as a massive "silent disaster"
NCDs
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a rare malignant tumor of the retina, affecting young children
retinoblastoma
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Malignant transformation, or carcinogenesis, has three step cellular process
initiation, promotion, progression
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a small vascular tumor of the adrenal medulla, causing irregular secretion of epinephrine and norepinephrine, leading to attacks of raised blood pressure, palpitations, and headache
pheochromocytoma
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The leading causes of cancer-related death in the United States in order of frequency and location in men
lung, prostate, and colorectal cancer
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4 phases of mitosis
prophase, metaphase, anaphase, telophase
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HIV causes an immune deficiency that makes people more susceptible to viral infection. Infection by a virus called _______ then appears to stimulate the development of Kaposi’s sarcoma
KSHV (Kaposi’s sarcoma-associated herpesvirus)
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These factors act by causing cell mutation or alteration in cell enzymes and proteins causing altered cell replication
chemical agents
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Each gene is coded for a specific product such as
protein and enzyme
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etiology/causative factors
viruses and bacteria, chemical carcinogens, dietary factors, physical stressors, hormonal factors, genetic and familial factors
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Agents that initiate or promote malignant transformation
carcinogens
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some common sarcomas
fat, bone, muscle
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Phase is where nuclear and cytoplasmic division occur.
mitosis
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what is wilm’s tumor name after
max wilms
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is a type of cancer that starts in the kidneys. It is the most common type of kidney cancer in children.
wilm’s tumor
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refers to the replacement of a mature, differentiated cell type by another mature, differentiated cell type that does not typically occur in the tissue in which it is found
metaplasia
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may be one of the multiple agents acting to initiate carcinogenesis
oncogenic viruses
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is the main cause of lung cancer and contributes to many other kinds of cancer as well
cigarette smoking