記憶度
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Complex, organic nitrogenous substances with very high molecular weights, found in all plant and animal cells, and consisting largely or entirely of alpha-amino acids united in peptide linkage
Protein
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Who stated that High molecular weight, composed of amino acids (block), Most important for us to live. a Join with peptide bonds and Alphabet of the protein structure
Proteios G.J Maider (1893)
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hindi mahaba, mababa yung molecular weight niya (12-50) para magbreak yung protein. May agents na ilalagay (Urea
Peptide.
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pwede ma lost yung biological activities through denaturation. Hindi mabbreak yung bond
Normal protein
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speed up reaction, metabolic processes. Hindi makukuha yung nutrients kung wala neto Possible maging malnourished
Enzyme.
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Transport and storage
Hemoglobin
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Coordinated motion
Actin, Myosin
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presence sa buhok and nails Capacity to make antibodies
Keratin
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Generation and transmission of nerve
Tryptophan , Vasoconstrictor
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repressor proteins. Silence specific DNA of a cells.
Control of growth and differentiation
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para magproduce ng hormone
Cell signaling
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insulin receptors
Membrane
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some of them are proteins/insulin. Thyrotropin, somatotropin - GH, LH, FSH.
Hormones
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What are the Simple Protein
Albumin , Globulin , Glutelin, Prolamine, Scleroprotein, Histone, Protamine
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What are the Conjugated Proteins
Nucleoprotein, Phosphoprotein, Glycoprotein, Chromoprotein, Lipoproteins, Metalloproteins
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Just amino acids only
Simple protein
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soluble water, heat coagulation
Albumin
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dilute alkali dilution
Globulin
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grass family, soluble, dilute, heat coagulated
Glutelin
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alcohol soluble choline
Promaline
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hair and nails (keratin)
Albuminoid
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basic protein (amino acid) soluble in water, dilute in alkali pwede makita sa DNA
Histone
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inaaxid alkali, spermatozoa
Protamine
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amino + nucleic acid
Nucleoprotein
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Glyco protein and muco protein (carbohydrates)
Nucleoprotein
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(phosphoric acid residue) casein casein (protein found in milk)
Phosphoprotein
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(gives color( eg. hemoglobin
Chromoprotein
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LDL, Chylomicrons, ULDL, HDL
Mycoprotein
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Example of metallic acid
insulin, cytochrome
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partial to complete hydrolysis acid alkalaine or enzyme.
Derived protein
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As slight change of protein molecule and properties.
Primary derived
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No hydrolysis of peptide bonds
Primary derived
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Na form if there is an progressive hydrolytic. Masyadong hydrolysis (complete
Secondary derived
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hindi nagcocoagulate
Hydrolytic products
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simpler in structure
Peptotse
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elongated (pahaba), top, insoluble in water, single access to form fiber, involved structural e.g collagen > from a matrix of bond and ligaments.
Fibrous
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chief structural component
Keratin
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This are enzyme maraming enzyme inside our body
Biological function
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Storage protein
ferritin, myoglobin
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protein hormones and dna binding proteins.
Regulatory
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inbricj and mortar roseor w function e.g elastin and proteoglycans.
Structural protein
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a part of your body in general kayo mismo; antibodies
Protective protein
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hemoglobin, blue transferrin, glycoprotein (HDL, LDL)
Transport proteins.
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muscle construction (actin, myosin)
Contractile
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hindi sya maclassify
Exorcistic
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protects the blood from fishing
Antartica fish
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wine/sa isang insect; perfect electricity (pakpak ng insekto)
Resilin
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Three dimensional arrangement of amino acids with the polypeptide chain in a corkscrew shape
Secondary Structure - Alpha Helix
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Polypeptide chains are arranged side by side Hydrogen bonds form between chains R groups of extend above and below the sheet Typical of fibrous proteins such as silk.
Secondary Structure - Beta Pleated Sheet
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Three polypeptide chains woven together Glycine, proline, hydroxyproline and hydroxylysine H bonding between -OH groups gives a strong structure. Typical of collagen, connective tissue, skin, tendons, and cartilar.
Secondary Structure - Triple Helix
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The building blocks of proteins
Amino Acids
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Any product derived from a living plant and animal source. The law refers to “any virus”, therapeutic serum, toxin, antitoxin or analogous product.
Biologicals
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What are the 2 General Categories of Biologics
Antibodies, Antigen
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A material that provokes the immune response
Antigen
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Found predominantly in serum fraction of the blood
Antibodies
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A specific immunity developed by an individual in response to the introduction of antigenic substances into the body
Active immunity
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Developed slowly but it is usually long lasting
Active immunity
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The immunity may be produced as the response to a series of injections( Typhoid or pertussis vaccine), thus stimulating the body cells to make their own
Artificially Acquired :
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Developed by introduction of preformed antibodies (not antigens) into the body
Passive Immunity
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the body cells are not stimulated to produce their own antibodies.
Passive Immunity
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Injection of immunizing biologics containing preformed antibodie
Artificially Acquired Passive Immunity
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It is used as inoculations to stimulate the production of antibodies.
Vaccines