問題一覧
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A chemical messenger that communicates across a synapse
neurotransmitter
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One of a group of chemical messengers that includes amino acid and amines
small molecule transmitters
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A peptide that acts as a neurotransmitter, neuro modulator, or a neurohormone
neuropeptide
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An essential component of proteins
amino acid
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This meet all or most of the proceeding criteria specified for neurotransmitters and play a vital role in neurotransmission
small molecule transmitters
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A major small molecule neurotransmitter used at the neuromuscular junction, in the ans, and in the cns
acetylcholine
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Results from the metabolic activities of mitochondria
acetyl coenzyme A (acetyl CoA)
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This enzyme acts on two building blocks, or precursors, to produce the ach
choline acetyltransferase (ChAT)
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an enzyme that breaks down the neurotransmitter ach
Acetylcholinesterase
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Neurons that release ach are said to be what?
cholinergic
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It is a major subtype of cholinergic receptors which is a postsynaptic receptor that responds nicotine and ach
nicotinic receptor
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It is a major subtype of cholinergic receptor where where in it is a postsynaptic receptor that responds to both ach and muscarine
muscarinic receptor
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One of the major of biogenic amine neurotransmitters, including dopamine, norepinephrine, epinephrine, and serotonin
monoamine
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A member of a group of related biogenic amines (dopamine, norephenamine, and epinephrine)
catecholamines
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One of the subgroup of monoamines (serotonin and melatonin)
indoleamine
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Within the axon terminal, monoamines that are not in case in vesicles are broken down by the action of the enzyme ____?
monoamine oxidase (MAO)
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Enzyme that breaks down monoamines
monoamine oxidase
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A substance produced during the synthesis of catecholamines that is also administered as a treatment for parkinson's disease
L-dopa
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A major monoamine and kate kolamine neurotransmitter implicated in motor control, reward, and psychosis
dopamine
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A major monoamine and catecholamine neurotransmitter
norepinephrine
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One of the monoamine/catecholamine neurotransmitters; also known as adrenaline
epinephrine
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It arises in the ventral pigmentum of the midbrain and projects to various part of the limbic system (hippocampus amygdala and nucleus accumbens). It participates in feelings of reward, and it plays on important role in addiction
mesolimic system
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It is a dopamine receptor subtypes wherein it serves as both post synaptic receptor and pre-synaptic auto receptors. This receptor class has been implicated in both reward and psychotic behavior
d2 receptors
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The most significant source of norepinephrine is the ______ of the pons
locus coeruleus
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A major monoamine an indoleamine neurotransmitter our believed to participate in regulating mood, sleep, and appetite
serotonin
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Serotonin synthesis begins with the dietary triatophan, which is converted into ___ by the action of ______.
5-HTP, trytophan hydroxylase
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5 htp is converted into serotonin by the action of____.
5-HTP decarboxylase
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Among the 20 basic amino acids that are used to build other proteins
glutamate
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A major excitatory neurotransmitter in the central nervous system
glutamate
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What are the three receptors of glutamate
N-methyl-D-aspartate (NMDA), alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA, kainate
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A major inhibitory amino acid neurotransmitter of the central nervous system
gamma aminobutyric acid (GABA)
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Gaba is a synthesized form of glutamate through the action of the enzyme ____?
glutamic acid decarbulase (gad)
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Gaba receptors
GABAa, BABAb
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Also acts as neurotransmitters in the cns and in connections between ans and vas deferens, bladder, heart, and gut.
adenosine
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A byproduct of adenosine triphosphate that functions as a neurotransmitter
adenosine
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A neurotransmitter that is involved with the perception of pain
adenosine
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It is a gaseous neurotransmitters that performs a type of signaling between neurons
nitric oxide
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it is a gaseous neurotransmitter involved with neural communication, the maintenance of blood pressure, and penile erection
nitric oxide
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A substance that promotes the activity of neurotransmitter
agonist
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A substance that reduces the action of neurotransmitter ( receptor blocker)
antagonist
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It is a drug that interferes with the production of dopamine, norepinephrine, and epinephrine
a-methyl-p-tyrosine( AMPT)
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A substance derived from a plant that deplet supplies of monoamines by interfering with the uptake of monoamines into synaptic vesicle; used to treat high blood pressure but often produces depression
reserpine
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A bacteria found in spoiled food, prevent the release of ach at the neuromuscular junction and at the synopsis of the autonomic nervous system.
clostridium botulinum
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It is a disease caused by a bacteria found in spoiled food and it leads rapidly to paralysis and death
botulism
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It is used to paralyzed muscles to prevent the formation of wrinkles and to treat a variety of medical conditions involving excess muscle tension
botox
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A substance derived from amazonian plants causes paralysis by blocking the nicotinic ach receptor
curare
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A major tranquilizer that acts as gaba agonist
benzodiazepine
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A drug that produces strong sedation by acting as a gaba agonist
barbiturate
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A substance that interferes with the transport of released neurotransmitter molecules back into pre-synaptic terminal (antidepressant medication fluoxetine)
react take inhibitor
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A brain stem area in which the blood brain barrier is more permeable, triggers vomiting in response to the detection of circulating toxin
area postrema
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Perceive benefit from inactive substance or procedures
placebo effect
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A research design in which neither the participant or the experiment knows whether the participant is receiving a drug or a placebo until after the research is concluded
double blind experiment
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The process in which more of a drug is needed to produce the same effect
tolerance
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The system occurs when certain addictive drugs are no longer administered or are administered in smaller quantities
withdrawal
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a compulsive craving for drug effects or other experience
addiction
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Adopaminergic structure belief to participate in reward and addiction
nucleus accumbens
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A stimulant drug found in coffee tea cola and chocolate that acts as antagonist to adenosine
caffeine
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A stimulant drug that is a major active component found in tobacco
nicotine
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A powerful addictive dopamine agonist derived from the leaves of coca plants of south america
cocaine
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A highly addictive drug that acts as a potent dopamine agonist
aphetamine
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Stimulate dopamine and norepinephrine release and inhibit the reuptake
methamphetamine
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Stimulates the release of serotonin
ecstasy MDMA
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An illegal liquid sedative that appears to affect the threshold of response for number of neurotransmitter
gamma hydroxybutyrate (ghb)
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These drugs are derived from opium puppy and stimulate endorphin receptors
opiates
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A compound extracted from opium used to treat pain
morphine
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An opium derivative used medicinally for cough suppression and pain relief
codeine
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Use medically to relieve pain or nausea to combat glaucoma (an eye disorder) and to increase appetite
cannabinoids
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A major ingredient of cannabis
tetrahydrocannabinol (THC)
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A natural occurring brain chemical that interacts with cannabinoid receptors
anandamine
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A possible candidate for naturally occurring cannabinoid in the nervous system
sn-2 arachidonate glycerol (2- AG)
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The source of two psychoactive substances, muscimol and ibotenic acid
amanita muscaria mushroom
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A green peyote cactus is a source for ___?
mescaline
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A hallucinogen that acts as antagonist at the nmda glutamate receptor
phencyclidine
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A hallucinogen drug that resembles serotonin
lysurgic acid diethylamide (LSD)
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P is a continued use of alcohol despite medical or social harm
alcoholism
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Alcoholism can lead indirectly to _____ in which the ability to form new memories is impaired
korsakoff's syndrome