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Genetics (lesson1,2,3)
  • Benedick Acuesta

  • 問題数 89 • 10/24/2023

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  • 1

    the biological science which deals with the mechanism of heredity and causes of variations in living beings.

    Genetics

  • 2

    the process by which characteristics are passed from parents to offspring so that all organisms resemble their ancestors.

    Heredity

  • 3

    -units of biological information -physical particles present inside living cells. -also units of inheritance

    Gene

  • 4

    Factors Affected by Genes (7)

    • Cell structure • Cell function • Organization of cells into tissues and organ • Phenotype • Reproduction • Adaptability • Behavior

  • 5

    all chemical substances necessary for bodily processes

    Chemical level

  • 6

    basic structural and functional units of an organism’s body

    Cellular level

  • 7

    group of cells that perform a specific function

    Tissue level

  • 8

    consists of 2 or more tissues that perform a particular function

    Organ level

  • 9

    association of organs that have a common function

    System level

  • 10

    Father of genetics

    Gregor Johann Mendel

  • 11

    Genetics is generally divided into four major subdivisions:

    *Classical, or Mendelian Genetics *Molecular genetics *Population genetics *Quantitative genetics

  • 12

    A discipline that describes how physical characteristics (traits) are passed along from one generation to another.

    Classical or Mendelian Genetics

  • 13

    The study of the chemical and physical structures of DNA, its close cousin RNA, and proteins. -also covers how genes do their jobs. structure and function of genes at the molecular level

    Molecular Genetics

  • 14

    A division of genetics that looks at the genetic makeup of larger groups. fate of genes in the population

    Population Genetics

  • 15

    A highly mathematical field that examines the statistical relationships between genes and the traits they encode. role of genetics and environmental factors in the inheritance of traits

    Quantitative Genetics

  • 16

    gene regulation during development

    Developmental Genetics

  • 17

    behavior of the chromosome

    Cytogenetics

  • 18

    genetic change within and between species

    Evolutionary Genetics

  • 19

    roles of enzymes / proteins (as a product of genetic processes)

    Biochemical Genetics

  • 20

    behavioral traits that are inherited

    Behavioral Genetics

  • 21

    Branches of Genetics (8)

    *Developmental Genetics *Cytogenetics *Molecular Genetics *Evolutionary Genetics *Biochemical Genetics *Behavioral Genetics *Population Genetics *Quantitative Genetics

  • 22

    • high yielding and pest resistant varieties of rice, corn, wheat, vegetables and fruits • advances in farm animal production (meat, milk, egg) through breeding • production of microbial strain for fast fermentation (fermented foods and processed food products)

    Genetic Improvement of Plants, Animals and Microorganisms

  • 23

    • diseases and abnormalities with genetic bases – diabetes, hemophilia, mental disorder, metabolic abnormalities (gene therapy)

    Medicine (Human and Veterinary medicine)

  • 24

    • inheritance of certain traits (desirable or undesirable) • pedigree analysis and pattern of inheritance (cause of genetic disorder)

    Genetic Counseling

  • 25

    • helps solve problems of disputed parentage and identifying criminals (DNA fingerprinting, ABO or MN blood types, enzyme markers)

    Legal and Forensic Applications

  • 26

    • production of different plants, animals, microorganisms or food that have been genetically enhanced through biotechnology

    Genetic Engineering/Biotechnology

  • 27

    the basic building blocks of all living things.

    Cell

  • 28

    separates the inside and the outside of the cell, and controls what goes in and comes out.

    Cell membrane

  • 29

    a jelly-like substance (cytosol) containing the cell’s parts.

    Cytoplasm

  • 30

    carries out a specific function in the cell.

    Organelles

  • 31

    a network of long fibers that make up the cell’s structural framework.

    Cytoskeleton

  • 32

    -helps process molecules created by the cell. -also transports these molecules to their specific destinations either inside or outside the cell.

    Endoplasmic reticulum

  • 33

    packages molecules processed by the endoplasmic reticulum to be transported out of the cell.

    Golgi apparatus

  • 34

    digest and dispose of unwanted protein, DNA, RNA, carbohydrates, and lipids in the cell. -t is referred to as the cell’s recycling center

    Lysosomes

  • 35

    single membrane–bound vesicles found in most eukaryotic cells. They contain several different enzymes and are involved in various metabolic pathways

    Peroxisomes

  • 36

    are complex organelles that convert energy from food into a form that the cell can use.

    Mitochondria

  • 37

    serves as the cell’s command center, sending directions to the cell to grow, mature, divide, or die. It also houses DNA (deoxyribonucleic acid), the cell’s hereditary material.

    Nucleus

  • 38

    the outer lining of the cell. It separates the cell from its environment and allows materials to enter and leave the cell.

    Plasma membrane/Cell membrane

  • 39

    are organelles that process the cell’s genetic instructions to create proteins. These organelles can float freely in the cytoplasm or be connected to the endoplasmic reticulum

    Ribosomes

  • 40

    are organelles that carry out photosynthesis, which makes the food plant cells need to live. This food is in the form of sugars

    Chloroplast

  • 41

    outside the cell membrane, and it provides structure for the cell.

    Cell wall

  • 42

    Prokaryotes vs Eukaryotes

    • Prokaryotic organisms are always unicellular and may be bacteria or archaea. *do not contain membrane bound organelles *do not have a nucleus; instead, they keep their DNA in a cell region called the nucleoid *prokaryotic cells are much smaller than eukaryotic cells • Eukaryotic organisms may be unicellular or multicellular and include plants, animals, fungi, and protists. *contains membrane bound organelles *Does have nucleus *Eukaryotic cells contain a variety of cell structures and organelles (mitochondria, golgi apparatus, endoplasmic reticulum, nuclei, lysosomes, chloroplast, etc.)

  • 43

    is the hereditary material in almost all organisms

    DNA or Deoxyribonucleic acid

  • 44

    Types of cell organelles (13)

    (1) nucleolus (2) nucleus (3) ribosome (4) vesicle (5) rough endoplasmic reticulum (6) Golgi apparatus (7) cytoskeleton (8) smooth endoplasmic reticulum (9) mitochondria (10) vacuole (11) cytosol (12) lysosome (13) centriole.

  • 45

    This PROCESS uses oxygen and simple sugars to create adenosine triphosphate (ATP), the cell’s main energy

    Oxidative phosphorylation

  • 46

    forms of the same gene with small differences in their sequence of DNA bases.

    Alelle

  • 47

    DNA molecule is packaged into thread-like structures

    Chromosomes

  • 48

    Each chromosome is made up of DNA tightly coiled many times around proteins called

    histones

  • 49

    Chromosome is visible during....

    Cell division

  • 50

    In humans, each cell normally contains___ pairs of chromosomes for a total of 46

    23

  • 51

    Twenty-two of these pairs, called....

    Autosomes

  • 52

    The 23rd pair called...

    Sex chromosomes

  • 53

    Levels of Compaction

    DNA - add Core histones - Nucleosome - beads on a string - add histone H1 - add scaffold proteins - chromatin - concentrated chromosomes

  • 54

    The material that makes up chromosomes, which we now know to be proteins and DNA

    Chromatin

  • 55

    more loosely packed, and tends to contain genes that are being transcribed

    Euchromatin

  • 56

    more densely compacted_________, which is rich in repetitive sequences and tends not to be transcribed.

    heterochromatin

  • 57

    prokaryotic vs eukaryotic chromosomes

    *prokaryotic cells typically have only a single, circular chromosome, they can replicate faster than eukaryotic cells. *prokaryotic cell can undergo two rounds of DNA replication before the cell, itself, has divided. *Since eukaryotic cells typically have multiple linear chromosomes, capped with telomeres, eukaryotic DNA replication and cell division (mitosis and meiosis) are a bit more complicated. *DNA replication occurs before mitosis begins, and it can’t occur while the cell is dividing. *Each time a typical or somatic eukaryotic cell divides, the telomeres get shorter

  • 58

    are typically pairs of similar, but non-identical, chromosomes in which one member of the pair comes from the male parent, and the other comes from the female parent.

    Homologous chromosomes

  • 59

    contain different gene loci, and are usually distinguishable based on cytological features such as length, centromere position, and banding patterns.

    Non-homologous chromosomes

  • 60

    is the complete set of chromosomes of an individual.

    karyotype

  • 61

    allows a geneticist to determine a person's karyotype - a written description of their chromosomes including anything out of the ordinary.

    Karyogram

  • 62

    Difference of haploid and diploid

    Haploid cells contain only one set of Chromosomes (n). Diploid, as the name indicates, contains two sets of chromosomes (2n).

  • 63

    the heritable condition of possessing more than two complete sets of chromosomes

    Polyploidy

  • 64

    An individual that contains one half the normal number of chromosomes

    Monoploid

  • 65

    two types of cell division..

    Mitosis and meiosis

  • 66

    Difference between mitosis and meiosis

    mitosis: *4 stages in total(plus interphase) *happens in somatic cells *Purpose is cellular proliferation *Produce 2 diploid daughter cells *chromosome number remains the same *Genetic variation doesn't change meiosis: *8 stages in total(plus interphase) *happens in germ cells *Purpose is sexual reproduction *produces 4 haploid daughter cells *Chromosome number is halved in each daughter cell *Genetic variation increased

  • 67

    Phases of mitosis (5)

    Interphase Prophase Metaphase Anaphase Telophase & Cytokinesis

  • 68

    phases of meiosis (9)

    Interphase Prophase I Metaphase I Anaphase I Telophase I & Cytokinesis Prophase II Metaphase II Anaphase II Telophase II & Cytokinesis

  • 69

    Mendels law of inheritance (3)

    Law of segregation Law of Dominance Law of Independent Assortment

  • 70

    defined as the process of how an offspring receives genetic information from the parent.

    Inheritance

  • 71

    2 main experiments to determine the laws of inheritance:

    1. Monohybrid Cross 2. Dihybrid Cross

  • 72

    hybrid of two individuals with homozygous genotypes which result in the opposite phenotype for a certain genetic trait

    Monohybrid Cross

  • 73

    cross of two traits, each having two alleles.

    Dihybrid cross

  • 74

    • Every parent’s pair of genes or alleles divide and a single gene passes from every parent to an offspring. • Which particular gene passes on in a pair is entirely up to chance.

    Law of segregation

  • 75

    • Recessive alleles are always masked by dominant alleles. • A cross between a homozygous recessive and a homozygous dominant shows the dominant phenotype by still having a heterozygous genotype. • This law could be explained by the monohybrid cross experiment. • In the case of a cross among the two organisms with contrasting traits, the character that is visible in the F1 generation is known as dominant and the one that is suppressed is known as recessive.

    Law of Dominance

  • 76

    • Discrete pairs of alleles pass onto the offspring without depending on one another. • The inheritance of genes at a particular region in a genome does not affect the inheritance of genes in a different region.

    Law of Independent Assortment

  • 77

    A specific position along a chromosome

    Locus

  • 78

    a condition wherein the dominant allele completely masks the effect of the recessive allele

    Complete Dominance

  • 79

    a form of intermediate inheritance in which one allele for a particular trait is not expressed completely over its paired allele

    Incomplete dominance

  • 80

    heterozygous individual expresses the phenotype of both alleles simultaneously.

    Co-dominance

  • 81

    Recommend the use of lenses for viewing small objects

    1485 Leonardo Da Vinci

  • 82

    Produced the first operational Microscope

    1590 Hans and Zacharias Janssen

  • 83

    Introduced the term "cell" and describe cork cells

    1665 Robert Hooke

  • 84

    Classified the tissues

    Marcello Malphigi

  • 85

    Classified biological organisms

    Carl Linnaeus

  • 86

    Founder of embryology

    Caspar Friedrich Wolff

  • 87

    coined the word "biology"

    Jean Baptiste Lamarck

  • 88

    discovered the nucleus in cells of flowering plants

    Robert brown

  • 89

    Coined the term "mitosis"

    Walther Flemming