問題一覧
1
It is a membrane attacking complex of the complement system:
C5-C9
2
Activation of the complement system by antibodies occurs:
during activation by the classical way
3
Opsonization:
the combination of the phagocytosed object with immunoglobulins and complement
4
III type hypersensitivity reactions are related to:
Arthus reaction.
5
III type of hypersensitivity reactions refers:
Acute poststreptococcal glomerulonephritis
6
Inactivated vaccines include:
from killed microorganisms
7
Live vaccines consist of:
from microorganisms with weakened virulence
8
Immunity formed after injection of immune serum:
is artificially acquired passive immunity
9
To prepare killed vaccines, it is used in the inactivation of microorganisms:
from chemical factors or high temperature
10
Live vaccines include:
from microorganisms with weakened virulence
11
Which conditions are more suitable for preparing live vaccines:
long-term cultivation in artificial nutrient media
12
Anatoxin can be used in the prevention of which disease?
diphtheria
13
Immune (anti) serum:
is a serum containing antibodies
14
Antitoxic serum is not used in the treatment of which disease:
enteric fever
15
Vaccines are obtained:
from microorganisms and their antigens
16
Recombinant vaccines are obtained by:
transfer of genes that ensure the synthesis of immunodominant antigens of microorganisms to producer cells through a vector
17
Injection of vaccines causes:
to the induction of a specific immune response
18
A man in his twenties presents in the emergency room withshortness of breath and fatigue. He is also very pale. Two daysearlier he was given penicillin for an infection. He had penicillinpreviously without problems and stated that he had “noallergy” to penicillin. Laboratory testing shows that antibodiesto penicillin are present in the patient’s serum and thathe is breaking down his own red blood cells. He is diagnosedwith immune hemolytic anemia. The patient has which type ofhypersensitivity reaction?
Type II
19
Which of the following laboratory assays can be used to detectthe number and types of immune cells in the peripheral blood?
Flow cytometry
20
Which one of the following laboratory assays is considered to bean in vitro counterpart of the type IV hypersensitivity reactionsseen in the TB skin test?
IFN-γ production by white blood cell (WBC) treated with TB antigen
21
IgE-mediated histamine release is classified as what type ofhypersensitivity reaction?
Type I
22
T cell associatedhypersensitivity reaction:
Type IV
23
A hypersensitivity reaction associated with a tuberculin reaction includes:
Type IV
24
Prepared from microorganisms with weakened virulence:
live vaccines
25
Chemical vaccines consist of:
individual antigens of a microbial cell
26
Recombinant vaccines are obtained by:
genetic engineering
27
Anatoxins consist of:
bacterial exotoxins that have lost their toxigenicity
28
For the preparation of toxoid:
0. 4% formaldehyde is added to bacterial exotoxins and incubated at 37°C for 3-4 weeks
29
Toxoids can be used to prevent what diseases:
diphtheria
30
Immune sera contain:
antibodies
31
The mechanism of therapeutic action of immune serum:
neutralization of the microbe or its toxin
32
Therapeutic and prophylactic effect of immune serum is associated with:
with specific antibodies
33
Immune serum is obtained:
from the blood of hyperimmunized animals
34
Antitoxic serums are not used in the treatment of what diseases?
typhoid fever
35
Serum are used:
in the serological identification of microorganisms
36
Serum are used:
in serological reactions
37
Vaccines are obtained from:
microorganisms and their antigens
38
Introduction of vaccines into the body:
leads to the induction of a specific immune response
39
Anaerobic bacteria such as B fragilis occur in the sigmoid colon in a concentration of about 1011/g of stool. At what concentration do facultative organisms such as E coli occur?
108/g
40
A 65-year-old woman was admitted with squamous cell carcinoma of the cervix. She underwent extensive gynecologic surgery and was maintained postoperatively on broad-spectrum intravenous antibiotics. The patient had a central venous catheter placed on the day of surgery. Beginning 3 days postoperatively, the patient became febrile. On day 8, cultures of blood and of the tip of the central line both grew gram-positive organisms that were ovoid and reproduced by budding. Which of the following microorganisms is most likely responsible for the patient’s condition?
C albicans
41
A 65-year-old woman was admitted with squamous cell carcinoma of the cervix. She underwent extensive gynecologic surgery and was maintained postoperatively on broad-spectrum intravenous antibiotics. The patient had a central venous catheter placed on the day of surgery. Beginning 3 days postoperatively, the patient became febrile. On day 8, cultures of blood and of the tip of the central line both grew gram-positive organisms that were ovoid and reproduced by budding. The most likely portal of entry for the organism is?
During placement of the central venous catheter
42
Certain microorganisms are never considered to be members of the normal flora. They are always considered to be pathogens. Which one of the following organisms fits into that category?
Mycobacterium tuberculosis
43
Which one of the following microorganisms can be part of the normal vaginal flora and cause meningitis in newborns?
Group B streptococci
44
S pneumoniae can be part of the normal flora of 5–40% of people. At what anatomic site can it be found?
Nasopharynx
45
Which of the following best describes the mechanism of action of diphtheria toxin?
Inhibits elongation factor 2
46
Which of the following statements is correct?
Lipopolysaccharide is part of the cell wall of E coli.
47
Which of the following statements about lipopolysaccharide is correct?
It interacts with macrophages and monocytes yielding release of cytokines.
48
Which two cytokines play an important role in attracting neutrophils to the site of an infection?
IL-8 and IL-17
49
IFN-α and IFN-β are produced by the virus-infected cell due to the interaction of virus nucleic acid with which of the following?
TLR pathway
50
What is a characteristic of the adaptive immune response and not of the innate response?
Clonal expansion of effector cells
51
Endoflagella is characteristic for:
Treponema
52
The motility is characterisic for:
Treponema
53
Disinfection is:
the destruction of pathogenic microorganisms
54
RNA - genome viruses:
paramyxoviruses
55
RNA - genome viruses:
orthomyxoviruses
56
RNA - genome viruses:
togaviruses
57
Used in microbiological investigation of air: 1) Flotation method 2) Filtration 3) Sedimentation 4) Aspiration
3, 4
58
Belong to sanitary-indicative microorganisms of air: 1) Escherichia coli 2) Bordetella pertussis 3) Staphylococcus aureus 4) Haemophilus influenzae
only 3
59
Determined when the sanitary-microbiological examination of soil: 1) Titr spore-forming bacteria; 2) General number of bacteria in one gram of soil; 3) Titr sanitary-indicative microorganisms; 4) Titr causative agent of anthrax;
2, 3
60
Sanitary-indicative microorganisms of soil: 1)Escherichia coli 2) Clostridium perfringens 3) Clostridium tetani 4) Bacillus anthracis
1, 2
61
Do not belong to the function of normal microflora:
participation in the respiration processes
62
Belong to sanitary-indicative microorganisms of water: 1) Escherichia coli 2) Clostridium perfringens 3) Clostridium tetani 4) Bacillus anthracis
only 1
63
The sensitivity of bacteria to antibiotics determined by disk diffusion method is evaluated based on:
the diameter of the sterile zone
64
The minimum bactericidal concentration of antibiotic is:
the least amount of antibiotic contributing to destruction of microorganisms
65
The minimum inhibitory concentration of antibiotic is:
the least amount of antibiotic for stopping the growth of microorganisms
66
The medium for cultivation of anaerobes:
Kitt-Tarozzi medium
67
Rickettsia, Chlamydia and Viruses:
are cultivated in cell culture
68
Is occurred in the stationary phase of bacterial growth:
the equality of dividing and dying cells
69
Persistence of viruses:
is the long-term storage in the host cell
70
Is cultivated in vivo: 1) Rickettsia 2) Chlamydia 3) Actinomyces 4) Mycoplasma 5) Viruses
1, 2, 5
71
During the passive diffusion nutrients penetrate into microbial cells:
due to the difference in osmotic pressure
72
What properties include the size and shape of bacterial cells?
morphological properties
73
Pure culture obtaining is based on:
the mechanical separation of bacterial cells
74
Culture characteristics of bacteria include:
the character of growth on nutrient media
75
The lag phase of bacterial growth includes:
adaptation to new environment
76
The pathological material from patient was inoculated to different nutrient media and incubated for 3 days at appropriate temperature using anaerobic jar. Which microorganisms will grow as a result?
obligate anaerobes and facultative anaerobes
77
Colonia of bacteria is:
the population of bacteria on solid media surface
78
The differential-diagnostic medium is used for:
detection of the biochemical activity for bacterial identification
79
Antiseptic medication of heavy metal salts:
silver nitrate
80
Which concentration of ethyl alcohol is used as antiseptic:
60-70%-solution
81
The mechanism of antimicrobial action of ethyl alcohol:
the denaturation of microbial protein
82
Antiseptic preparation from the dyes group:
ethacridine lactate
83
Antiseptic medication of halogens:
tincture iodine
84
Elimination of microorganisms from the skin, mucous membranes and wound surfaces is called:
antisepsis